Hľadali ste: Biosensis

Katalógové číslo: (BSENR-175-20)

Dodávateľ: BIOSENSIS PTY

Opis: NT3 is a member of the neurotrophin family, that controls survival and differentiation of visceral and proprioceptive sensory neurons. NT3 is closely related to both NGF and BDNF. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NT3-deficient mice generated by gene targeting display sevvere movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Brain and peripheral tissues. SIMILARITY: Belongs to the NGF-beta family.

Merná jednotka: 1 * 20 µG

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Katalógové číslo: (BSENR-1495-50)

Dodávateľ: BIOSENSIS PTY

Opis: Endomorphins 1 and 2 are endogenous opioid peptides which have the highest affinity for the mu-opioid receptors. Located in various parts of the brain and interacts with mu-opioid receptors and produces analgesia.

Merná jednotka: 1 * 50 µG

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Katalógové číslo: (BSENC-1386-50)

Dodávateľ: BIOSENSIS PTY

Opis: Neurofilaments contain three intermediate filament proteins: light (68 kDa), medium (160 kDa) and heavy (200 kDa). Neurofilament heavy (NF200 or NF-H) is phosphorylated and it is thought that this results in the formation of interfilament cross bridges that are important in the maintenance of axonal caliber. This antibody binds primarily to the phosphorylated axonal forms of NF-H.

Merná jednotka: 1 * 50 µl

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Katalógové číslo: (BSENC-1526-500)

Dodávateľ: BIOSENSIS PTY

Opis: CNTF is a survival promoting factor for different types of neurons in vitro and in vivo. The essential structural features for the biological function of human CNTF were investigated by Thier, M. et al. They showed that deletion of 14 N-terminal and 18 C-terminal amino acids significantly increased bioactivity compared to wild-type CNTF. FUNCTION: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Nervous system. PHARMACEUTICAL: CNTF is being tested under the name Axokine by Regeneron Pharmaceuticals for treatment of human motor neuron diseases, such as amyotrophic lateral sclerosis (ALS). As it induces substantial weight loss, preferentially of fat as opposed to lean body mass, it is being used for obesity treatment. SIMILARITY: Belongs to the CNTF family.

Merná jednotka: 1 * 500 µl

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Katalógové číslo: (BSENM-1301-100)

Dodávateľ: BIOSENSIS PTY

Opis: The D-tag system utilises a short hydrophilic peptide (DYKDDDDK) that is fused to either the N- or C-terminus of the protein of interest. It can be used in conjunction with other tags such as the 6X His tag.

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (BSENM-1309-100)

Dodávateľ: BIOSENSIS PTY

Opis: The Human influenza hemagglutin (HA) tag corresponds to a region (98-106 amino acids) from the HA molecule.

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (BSENM-1306-100)

Dodávateľ: BIOSENSIS PTY

Opis: GST (Glutathione S-Transferase) is a 26 kDa protein encoded by the Schistosoma japonicum.

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (BSENM-1320-100)

Dodávateľ: BIOSENSIS PTY

Opis: Recognizes native and denatured forms of Green Fluorescent Protein (GFP) and its variants: Enhanced Green Fluorescent Protein (EGFP), Yellow Fluorescent Protein (YFP), Enhanced Yellow Fluorescent Protein (EYFP) and Cyan Fluorescent Protein (CFP).

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (BSENS-059-500)

Dodávateľ: BIOSENSIS PTY

Opis: FUNCTION: Target-derived survival factor for peripheral sensory sympathetic neurons. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues. SIMILARITY: Belongs to the NGF-beta family.

Merná jednotka: 1 * 500 µG

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Katalógové číslo: (BSENR-102-500)

Dodávateľ: BIOSENSIS PTY

Opis: FUNCTION: Target-derived survival factor for peripheral sensory sympathetic neurons. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues. SIMILARITY: Belongs to the NGF-beta family.

Merná jednotka: 1 * 500 µG

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Katalógové číslo: (BSENR-1556-100)

Dodávateľ: BIOSENSIS PTY

Opis: The elF2c (Argonaute, Ago) protein is a core protein of the RNA-induced silencing complex (RISC).

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BSENR-075-100)

Dodávateľ: BIOSENSIS PTY

Opis: Alpha synuclein is an abundant 140 amino acid neuronal protein, expressed primarily at presynaptic terminals in the central nervous system. FUNCTION: May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase 3 activation. TISSUE SPECIFICITY: Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.SUBUNIT: Soluble monomer which can form filamentous aggregates. Interacts with UCHL1. Interacts with phospholipase D and histones. SUBCELLULAR LOCATION: Cytoplasm. Membrane. Nucleus. Note=Membrane-bound in dopaminergic neurons. Also found in the nucleus. ALTERNATIVE PRODUCTS: 3 named isoforms produced by alternative splicing. Additional isoforms seem to exist.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BSENC-1534-500)

Dodávateľ: BIOSENSIS PTY

Opis: Presenilin-1 (PSEN1) is a multi-pass membrane protein and component of the gamma-secretase complex. PSEN1 is thought to play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may also play a role in hematopoiesis. Defects in PSEN1 are a cause of Alzheimer disease type 3 (AD3), a familial early-onset form of Alzheimer disease (Ref:SWISS-Prot).

Merná jednotka: 1 * 500 µl

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Katalógové číslo: (BSENM-1314-100)

Dodávateľ: BIOSENSIS PTY

Opis: The Myc tag contains the amino acids Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu (E-Q-K-L-I-S-E-E-D-L) corresponding to amino acids 410-419 of human Myc. This tag is widely used for monitoring expression of recombinant proteins in bacteria, insect and mammalian cells.

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (BSENM-1573-100)

Dodávateľ: BIOSENSIS PTY

Opis: Protein DJ-1 has many roles including protecting cells against oxidative stress and cell death (Ref: SwissProt). Mutations in the DJ-1 gene have been associated with rare forms of autosomal recessive early-onset Parkinson's disease.

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (BSENR-1683-500)

Dodávateľ: BIOSENSIS PTY

Opis: Beta-synuclein is a soluble cytoplasmic protein associated with synaptic vesicles and a member of the synuclein family. Mutations in alpha-synuclein cause early onset Parkinson's disease. Expression of beta synuclein may modulate alpha-synuclein aggregation found in Parkinson's disease.

Merná jednotka: 1 * 500 µG

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