Hľadali ste: Biosensis

Dodávateľ: BIOSENSIS PTY

Opis: Fluoro-Jade stain is a fluorochrome derived from fluorescein, and is commonly used in neuroscience disciplines to label degenerating neurons in ex vivo tissue of the central nervous system.

KBÚ – slovenskú verziu si vyžiadajte na regulatory.cz@avatorsciences.com

Katalógové číslo: (BSENR-1687-100)

Dodávateľ: BIOSENSIS PTY

Opis: Adenylate cyclases are enzymes which interact with and are activated by the GTP bound alpha subunits of trimeric G-proteins. Activated adenylate cyclases are responsible for the production of the important "second messenger" signalling molecule cyclic-AMP, which is generated from ATP. The type III adenylate cyclase enzyme is localized in the membranes surrounding the cilia in neurons, and our antibody is an excellent marker of neuronal cilia in the brain and in cells in tissue culture. Adenylate cyclase type III is a large complex molecule of, in the human, 1145 amino acids with a deduced molecular weight of 129kDa. The protein may be variably glycosylated, so that on SDS-PAGE and western blots it runs as a diffuse band of about 160kDa in cortex and about 200kDa in olfactory epithelium. The molecule has a complex structure, with 12 transmembrane domains and two cyclase domains. Each cyclase domain is immediately C-terminal to 6 transmembrane segments, but only the second, C-terminal cyclase is believed to be catalytically active.

Merná jednotka: 1 * 100 µG

Predaj

Katalógové číslo: (BSENM-1837-100)

Dodávateľ: BIOSENSIS PTY

Opis: Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation (Ref: uniprot.org).

Merná jednotka: 1 * 100 µG

Predaj

Katalógové číslo: (BSENM-1690-100)

Dodávateľ: BIOSENSIS PTY

Opis: Anti-LAMP1 Mouse T4 Antibody [clone: 5H6]

Merná jednotka: 1 * 100 µG

Predaj

Katalógové číslo: (BSENM-1693-100)

Dodávateľ: BIOSENSIS PTY

Opis: Anti-ALDOC Mouse T4 Antibody [clone: 4A9]

Merná jednotka: 1 * 100 µG

Predaj

Katalógové číslo: (BSENM-1809-100)

Dodávateľ: BIOSENSIS PTY

Opis: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). Ref: uniprot.org

Merná jednotka: 1 * 100 µG

Predaj

Katalógové číslo: (BSENC-1795-50)

Dodávateľ: BIOSENSIS PTY

Opis: May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Ref: uniprot.org.

Merná jednotka: 1 * 50 µG

Predaj

Katalógové číslo: (BSENC-1804-50)

Dodávateľ: BIOSENSIS PTY

Opis: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. Ref: uniprot.org

Merná jednotka: 1 * 50 µl

Predaj

Katalógové číslo: (BSENM-1815-100)

Dodávateľ: BIOSENSIS PTY

Opis: Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins (PubMed:10926528, PubMed:12044163, PubMed:11972040, PubMed:16908857, PubMed:16586416, PubMed:17060607, PubMed:17449675, PubMed:18818650, PubMed:21389983, PubMed:22198838, PubMed:23579341, PubMed:25205354, PubMed:27458239). Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (PubMed:1396673, PubMed:15111114). Ref: uniprot.org

Merná jednotka: 1 * 100 µG

Predaj

Katalógové číslo: (BSENBEK-2237-2P)

Dodávateľ: BIOSENSIS PTY

Opis: Biosensis proBDNF (Brain-derived neurotrophic factor, BDNF, Abrineurin) RapidTM enzyme-linked immunosorbent assay (ELISA) Kit is a sandwich ELISA that allows the specific, fast and reliable quantification of proBDNF in less than 4 hours in cell culture supernatants, human serum and EDTA-plasma only if used as directed. Please refer to the kit protocol for specific use instructions for each substrate application, in particular human blood samples.

Merná jednotka: 1 * 1 KIT

Predaj

Katalógové číslo: (BSENPE-001-100)

Dodávateľ: BIOSENSIS PTY

Opis: Saporin is a ribosome-inactivating protein (RIP) of type I. This monomeric RNA N-glycosidase purified from seeds of the plant Saponaria officinalis also known as Soapwort, is capable of specific depurination of eukaryotic ribosomes thus arresting protein synthesis. No ligand has been identified in saporin hence its inability to transverse the cell membrane. Due to its toxicity and stability of the structure, saporin has proven extremely useful for construction of immunotoxins.

Merná jednotka: 1 * 100 µG

Predaj

Dodávateľ: BIOSENSIS PTY

Opis: TrkA is a member of the neurotrophic tyrosine kinase receptor family. It is a membrane-bound receptor that upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TrkA is required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). TrkA leads to cell differentiations and may play a role in specifying sensory neuron subtypes. It has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. SUBUNIT: Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures. SUBCELLULAR LOCATION: TrkA is a heavily glycosylated transmembrane protein and contains 13 potential N-linked glycosylation sites. The TrkA-Fc chimera has N-linked and may have O-linked oligosaccharides.

Dodávateľ: BIOSENSIS PTY

Opis: The Biosensis NT3 Rapid™ enzyme-linked immune-sorbent assay (ELISA) kit is a sandwich ELISA that allows the specific, fast and reliable quantification of NT3 in less than 4 hours in cell culture supernatants and human plasma (EDTA and citrate) only if used as directed.

Dodávateľ: BIOSENSIS PTY

Opis: The Biosensis GDNF RapidTM enzyme-linked immunosorbent assay (ELISA) Kit is a sandwich ELISA that allows the quantification of GDNF in less than 4 hours in cell culture supernatants, cell lysates, and serum only if used as directed. Please refer to the kit protocol for specific use instructions for each substrate application, in particular mouse serum samples.

Katalógové číslo: (BSENBEK-2227)

Dodávateľ: BIOSENSIS PTY

Opis: The Biosensis Multi-Neurotrophin Rapid™ Screening ELISA Kit has been designed to allow rapid screening and quantification of NGF, BDNF, NT3 and NT4/5 in cell culture supernatants, lysates, serum, plasma (EDTA and citrate) and brain extracts only if used as directed.

Merná jednotka: 1 * 192 Tests

Predaj

Katalógové číslo: (BSENM-1560-100)

Dodávateľ: BIOSENSIS PTY

Opis: Lipid phosphate phosphohydrolase 3 (LPP3) is a member of the phosphatidic acid phosphatase (PAP) family. LPP3 catalyzes the conversion of phosphatidic acid to diacylglycerol. In addition it hydrolyzes lysophosphatidic acid, ceramide-1-phosphate and sphingosine-1-phosphate (Ref: SWISSPROT).

Merná jednotka: 1 * 100 µG

Predaj