Hľadali ste: Biosensis

Katalógové číslo: (BSENR-173-500)

Dodávateľ: BIOSENSIS PTY

Opis: Arc (also termed activity-regulated cytoskeleton-associated protein or Arg3.1), is an effector immediate early gene whose upregulation has been demonstrated during events of synaptic plasticity. Arg3.1 expression is detectable in neuronal cell bodies and dendrites in the brain regions including striatum and cortex hippocampus, hypothalamus, amygdala.

Merná jednotka: 1 * 500 µG

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Katalógové číslo: (BSENR-1313-100)

Dodávateľ: BIOSENSIS PTY

Opis: Maltose binding protein (MBP) is encoded by the malE gene of E.coli. MBP is often used in protein expression studies because it creates a stable fusion product that does not appear to interfere with the bioactivity of the protein of interest. It also allows for its easy purification from bacterial extracts under mild conditions.

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (BSENM-1314-100)

Dodávateľ: BIOSENSIS PTY

Opis: The Myc tag contains the amino acids Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu (E-Q-K-L-I-S-E-E-D-L) corresponding to amino acids 410-419 of human Myc. This tag is widely used for monitoring expression of recombinant proteins in bacteria, insect and mammalian cells.

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (BSENM-1573-100)

Dodávateľ: BIOSENSIS PTY

Opis: Protein DJ-1 has many roles including protecting cells against oxidative stress and cell death (Ref: SwissProt). Mutations in the DJ-1 gene have been associated with rare forms of autosomal recessive early-onset Parkinson's disease.

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (BSENM-1572-100)

Dodávateľ: BIOSENSIS PTY

Opis: 14.3.3 protein eta or 14.3.3  binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (Ref SwissProt). 14.3.3 protein eta is widely expressed as both homodimers and heterodimers and are concentrated in the nervous system. High concentrations of 14.3.3 protein eta have been linked to Creutzfeld Jacob Disease, Parkinson's Disease and early-onset schizopherenia.

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (BSENC-1409-50)

Dodávateľ: BIOSENSIS PTY

Opis: Vimentins are class-III intermediate filaments specific to mesenchymal tissue. Vimentin is an important cytoskeletal component responsible for maintaining cell integrity and has a probable role in the intracellular transport of proteins such as lipoproteins between the nucleus and plasma membrane. Immunohistochemical staining for Vimentin is characteristic of sarcomas. 

Merná jednotka: 1 * 50 µl

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Katalógové číslo: (BSENM-1391-50)

Dodávateľ: BIOSENSIS PTY

Opis: Neurofilaments are composed of three intermediate filament proteins: light (~68 kDa), medium (~160 kDa) and heavy (~200 kDa), which are involved in the maintenance of the neuronal caliber. Neurofilament light (NF68 or NF-L) is the most abundant of the three proteins.

Merná jednotka: 1 * 50 µl

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Katalógové číslo: (BSENR-1547-100)

Dodávateľ: BIOSENSIS PTY

Opis: Lysine acetylation of histones and non-histone proteins plays an important part in many cellular processes such as chromatin and nuclear signaling, transcription, gene silencing, cell cycle progression, apoptosis, differentiation, DNA replication and repair.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BSENC-1531-100)

Dodávateľ: BIOSENSIS PTY

Opis: FUNCTION: Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity. SUBCELLULAR LOCATION: Endoplasmic reticulum; rough endoplasmic reticulum. Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses. SIMILARITY: Belongs to the orexin family.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BSENM-1325-100)

Dodávateľ: BIOSENSIS PTY

Opis: Clone OX-42 recognises the rat equivalent of human CD11b. CD11b is a single-pass type I membrane protein that belongs to the integrin alpha chain family. CD11b is predominantly expressed in monocytes and granulocytes and is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles (Ref: SWISSPROT). CD11b is also frequently used as a microglial marker allowing to distinguish between quiescent and activated microglia based on the intensity of CD11b staining.

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (BSENM-1376-250)

Dodávateľ: BIOSENSIS PTY

Opis: Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH) is a metabolic enzyme responsible for catalyzing one step in the glycolytic pathway, the reversible oxidative phosphorylation of glyceraldehyde 3-phosphate. GAPDH may have other roles in the activation of transcription and in the regulation of apoptosis as well as Alzheimer's disease and Huntington's disease. The immunogen used to raise this particular antibody was extensively purified pig GAPDH. This antibody can be used as a loading control for western blotting experiments, allowing comparison between the level of this protein and others in a cell or tissue.

Merná jednotka: 1 * 250 µl

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Katalógové číslo: (BSENR-099-500)

Dodávateľ: BIOSENSIS PTY

Opis: FUNCTION: Seems to promotes the survival of visceral and proprioceptive sensory neurons. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Brain and peripheral tissues. SIMILARITY: Belongs to the NGF-beta family.

Merná jednotka: 1 * 500 µG

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Dodávateľ: BIOSENSIS PTY

Opis: The Biosensis Neurotrophin 4/5 Rapid™ enzyme-linked immunosorbent assay (ELISA) kit is a sandwich ELISA that allows the specific, fast and reliable quantification of NT4/5 in less than 4 hours in cell culture supernatants, human citrate-plasma and brain extracts only if used as directed.

Katalógové číslo: (BSENR-1683-500)

Dodávateľ: BIOSENSIS PTY

Opis: Beta-synuclein is a soluble cytoplasmic protein associated with synaptic vesicles and a member of the synuclein family. Mutations in alpha-synuclein cause early onset Parkinson's disease. Expression of beta synuclein may modulate alpha-synuclein aggregation found in Parkinson's disease.

Merná jednotka: 1 * 500 µG

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Katalógové číslo: (BSENR-1621-100)

Dodávateľ: BIOSENSIS PTY

Opis: This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (BSENR-1680-500)

Dodávateľ: BIOSENSIS PTY

Opis: Presenilin-1 (PSEN1) is a multi-pass membrane protein and component of the gamma-secretase complex. PSEN1 is thought to play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may also play a role in hematopoiesis. Defects in PSEN1 are a cause of Alzheimer disease type 3 (AD3), a familial early-onset form of Alzheimer disease (Ref:SWISS-Prot).

Merná jednotka: 1 * 500 µG

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