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Katalógové číslo: (BOSSBS-9850R-A680)
Dodávateľ: BIOSS INC
Opis: IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells. Acts as a direct physical tether, holding virions to the cell membrane and linking virions to each other. The tethered virions can be internalised by endocytosis and subsequently degraded or they can remain on the cell surface. In either case, their spread as cell-free virions is restricted. Its target viruses belong to diverse families, including retroviridae: human immunodeficiency virus type 1 (HIV-1), human immunodeficiency virus type 2 (HIV-2), simian immunodeficiency viruses (SIVs), equine infectious anemia virus (EIAV), feline immunodeficiency virus (FIV), prototype foamy virus (PFV), Mason-Pfizer monkey virus (MPMV), human T-cell leukaemia virus type 1 (HTLV-1), Rous sarcoma virus (RSV) and murine leukaemia virus (MLV), flavivirideae: hepatitis C virus (HCV), filoviridae: ebola virus (EBOV) and marburg virus (MARV), arenaviridae: lassa virus (LASV) and machupo virus (MACV), herpesviridae: kaposis sarcoma-associated herpesvirus (KSHV), rhabdoviridae: vesicular stomatitis virus (VSV), orthomyxoviridae: influenza A virus, and paramyxoviridae: nipah virus. Can inhibit cell surface proteolytic activity of MMP14 causing decreased activation of MMP15 which results in inhibition of cell growth and migration. Can stimulate Signalling by LILRA4/ILT7 and consequently provide negative feedback to the production of IFN by plasmacytoid dendritic cells in response to viral infection. Plays a role in the organization of the subapical actin cytoskeleton in polarized epithelial cells.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-0219R-CY5.5)
Dodávateľ: BIOSS INC
Opis: Core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. Modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit. Also regulates many host cellular functions such as signaling pathways and apoptosis. Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. Plays an important role in virus-mediated cell transformation leading to hepatocellular carcinomas. Interacts with, and activates STAT3 leading to cellular transformation. May repress the promoter of p53, and sequester CREB3 and SP110 isoform3/Sp110b in the cytoplasm. Also represses cell cycle negative regulating factor CDKN1A, thereby interrupting an important check point of normal cell cycle regulation. Targets transcription factors involved in the regulation of inflammatory responses and in the immune response: suppresses NK-kappaB activation, and activates AP-1. Mediates apoptotic pathways throught association with TNF-type receptors TNFRSF1A and LTBR, although its effect on death receptors-induced apoptosis remains controvertial. Enhances TRAIL mediated apoptosis, suggesting that it might play a role in mediated apoptosis, suggesting that it might play a role in immune-mediated liver cell injury. Secreted core protein is able to bind C1QR1 at the T-cell surface, resulting in down-regulation of T-lymphocytes proliferation. May transactivate human MYC, Rous sarcoma virus LTR, and SV40 promoters. May suppress the human FOS and HIV-1 LTR activity. May alter lipid metabolism by interacting with hepatocellular proteins involved in lipid accumulation and storage.
Merná jednotka: 1 * 100 µl


Nové řešení transparentnosti pro evropské zákazníky

Všimli jste si naší nově zlepšené viditelnosti rozmístění zásob u pokladny?

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Zlepšení rozmístění zásob

Katalógové číslo: (BOSSBS-0219R-HRP)
Dodávateľ: BIOSS INC
Opis: Core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. Modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit. Also regulates many host cellular functions such as signaling pathways and apoptosis. Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. Plays an important role in virus-mediated cell transformation leading to hepatocellular carcinomas. Interacts with, and activates STAT3 leading to cellular transformation. May repress the promoter of p53, and sequester CREB3 and SP110 isoform3/Sp110b in the cytoplasm. Also represses cell cycle negative regulating factor CDKN1A, thereby interrupting an important check point of normal cell cycle regulation. Targets transcription factors involved in the regulation of inflammatory responses and in the immune response: suppresses NK-kappaB activation, and activates AP-1. Mediates apoptotic pathways throught association with TNF-type receptors TNFRSF1A and LTBR, although its effect on death receptors-induced apoptosis remains controvertial. Enhances TRAIL mediated apoptosis, suggesting that it might play a role in mediated apoptosis, suggesting that it might play a role in immune-mediated liver cell injury. Secreted core protein is able to bind C1QR1 at the T-cell surface, resulting in down-regulation of T-lymphocytes proliferation. May transactivate human MYC, Rous sarcoma virus LTR, and SV40 promoters. May suppress the human FOS and HIV-1 LTR activity. May alter lipid metabolism by interacting with hepatocellular proteins involved in lipid accumulation and storage.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-0219R-A555)
Dodávateľ: BIOSS INC
Opis: Core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. Modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit. Also regulates many host cellular functions such as signaling pathways and apoptosis. Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. Plays an important role in virus-mediated cell transformation leading to hepatocellular carcinomas. Interacts with, and activates STAT3 leading to cellular transformation. May repress the promoter of p53, and sequester CREB3 and SP110 isoform3/Sp110b in the cytoplasm. Also represses cell cycle negative regulating factor CDKN1A, thereby interrupting an important check point of normal cell cycle regulation. Targets transcription factors involved in the regulation of inflammatory responses and in the immune response: suppresses NK-kappaB activation, and activates AP-1. Mediates apoptotic pathways throught association with TNF-type receptors TNFRSF1A and LTBR, although its effect on death receptors-induced apoptosis remains controvertial. Enhances TRAIL mediated apoptosis, suggesting that it might play a role in mediated apoptosis, suggesting that it might play a role in immune-mediated liver cell injury. Secreted core protein is able to bind C1QR1 at the T-cell surface, resulting in down-regulation of T-lymphocytes proliferation. May transactivate human MYC, Rous sarcoma virus LTR, and SV40 promoters. May suppress the human FOS and HIV-1 LTR activity. May alter lipid metabolism by interacting with hepatocellular proteins involved in lipid accumulation and storage.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-2113R-HRP)
Dodávateľ: BIOSS INC
Opis: Core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. Modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit. Also regulates many host cellular functions such as signaling pathways and apoptosis. Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. Plays an important role in virus-mediated cell transformation leading to hepatocellular carcinomas. Interacts with, and activates STAT3 leading to cellular transformation. May repress the promoter of p53, and sequester CREB3 and SP110 isoform3/Sp110b in the cytoplasm. Also represses cell cycle negative regulating factor CDKN1A, thereby interrupting an important check point of normal cell cycle regulation. Targets transcription factors involved in the regulation of inflammatory responses and in the immune response: suppresses NK-kappaB activation, and activates AP-1. Mediates apoptotic pathways throught association with TNF-type receptors TNFRSF1A and LTBR, although its effect on death receptors-induced apoptosis remains controvertial. Enhances TRAIL mediated apoptosis, suggesting that it might play a role in mediated apoptosis, suggesting that it might play a role in immune-mediated liver cell injury. Secreted core protein is able to bind C1QR1 at the T-cell surface, resulting in down-regulation of T-lymphocytes proliferation. May transactivate human MYC, Rous sarcoma virus LTR, and SV40 promoters. May suppress the human FOS and HIV-1 LTR activity. May alter lipid metabolism by interacting with hepatocellular proteins involved in lipid accumulation and storage.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (PRSI79-358)
Dodávateľ: PROSCI
Opis: An antiphosphotyrosine antibody was used to identify proteins that are phosphorylated in Rous sarcoma virus-transformed chick embryo fibroblasts, and a 76-kD protein was obtained that localizes to focal adhesions at the ends of actin-containing stress fibers in nontransformed cells. This protein was purified from chicken gizzard smooth muscle, and was named Pxn (Paxillin) ('paxillus' means 'small stake' or 'peg' in Latin) as a protein tethered to the membrane at focal adhesions
Merná jednotka: 1 * 100 µG


Katalógové číslo: (PRSI79-470)
Dodávateľ: PROSCI
Opis: An antiphosphotyrosine antibody was used to identify proteins that are phosphorylated in Rous sarcoma virus-transformed chick embryo fibroblasts, and a 76-kD protein was obtained that localizes to focal adhesions at the ends of actin-containing stress fibers in nontransformed cells. This protein was purified from chicken gizzard smooth muscle, and was named Pxn (Paxillin) ('paxillus' means 'small stake' or 'peg' in Latin) as a protein tethered to the membrane at focal adhesions
Merná jednotka: 1 * 100 µG


Dodávateľ: 3M
Opis: Opakovaně použitelné špunty do uší E-A-R™ Express™ jsou rozpoznatelné žluté a modré špunty do uší s pěnovou špičkou, která je tvarovaná a dimenzovaná pro pohodlné nošení. Mohou snížit hladinu hluku o 28 dB a mají hygienickou vkládací rukojeť.

Katalógové číslo: (DRAE6810690)
Dodávateľ: Dräger
Opis: Accessories for Alcotests
Merná jednotka: 1 * 100 items


Katalógové číslo: (113-0713)
Dodávateľ: VWR Collection
Opis: Tato obličejová maska ​​s nosním můstkem je vyrobena z dvouvrstvého netkaného PP.
Merná jednotka: 1 * 50 items


Dodávateľ: VWR Collection
Opis: Obličejové masky vyrobené ze 3 vrstev netkaného PP s nosním můstkem a ušními smyčkami nebo zavazovačkami.

Dodávateľ: GA
Opis: <p>Cryogenic direct thermal labels intended for labeling already frozen surfaces and containers under deep-freeze conditions, as low as (–80 °C).</p>

New Product

Dodávateľ: VWR Collection
Opis: Rychlý a jednoduchý test pro hygienickou kontrolu čistoty pracovních povrchů. Tento test lze dobře uplatnit v potravinářském průmyslu, ve stravovacím odvětví, mlékárenském průmyslu, na zdravotních úřadech a pro konzultanty HACCP. Barevná stupnice pro vyhodnocení testu je vytištěna na každém zkumavce. Porovnání mezi barvou roztoku a barevnou stupnicí potvrdí, jestli je zkoumaný povrch čistý nebo špinavý. Pro provedení testu postačí přetřít pruhem navlhčeného tampónu po zkoumaném povrchu a pak ho ponořit do zkumavky. Rozbijte skleněnou vialku s roztokem umístěnou uvnitř zkumavky pomocí svorky. Po dokončení testu je možné zkumavku zlikvidovat společně s komunálním odpadem. Zkumavky s testem by měly být skladovány při pokojové teplotě.
Dodávateľ: GA
Opis: <p>Thermal transfer cryogenic labels that will firmly adhere to both ambient and already frozen surfaces (as low as -80 °C) without the need for thawing, cure time, or any other special treatment prior to long-term storage in liquid nitrogen (–196 °C).</p>

New Product

Katalógové číslo: (115-1649)
Dodávateľ: Essity
Opis: Mdlo tekut Extra. Hygienick HD 1 * 6 KS
Merná jednotka: 1 * 6 items

New Product


Katalógové číslo: (115-1693)
Dodávateľ: Essity
Opis: Zsobnk na hygienick sky bl B5 1 * 8 KS
Merná jednotka: 1 * 8 items

New Product


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