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Katalógové číslo: (PRSI31-236)
Dodávateľ: PROSCI
Opis: POU5F1 is a POU transcription factor expressed by early embryo cells and germ cells. It determines paracrine growth factor signaling from stem cells to the trophectoderm
Merná jednotka: 1 * 100 µG


Katalógové číslo: (BOSSBS-11794R-FITC)
Dodávateľ: BIOSS INC
Opis: GHRH-R is a seven transmembrane domain protein that localizes to the somatotroph of the pituitary. GHRH-R plays an important role in growth and acts as a high-affinity receptor for GHRH. Binding of GHRH leads to the coupling of GHRH-R to G-protein which stimulates increased adenylyl cyclase activity and the accumulation of cAMP leading to the synthesis and release of growth hormone and somatotroph proliferation. In addition, this signalling pathway may have direct action in fetal/placental development, reproduction and immune function. GHRH and GHRH-R may also play a role in the regulation of non-rapid eye movement sleep (NREMS). The expression of GHRH-R is dependent on the presence of the POU domain factor Pit-1. Mutations in the gene encoding this protein can result in isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, and anterior pituitary hypoplasia (APH).
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-8867R-A647)
Dodávateľ: BIOSS INC
Opis: GHRH-R is a seven transmembrane domain protein that localizes to the somatotroph of the pituitary. GHRH-R plays an important role in growth and acts as a high-affinity receptor for GHRH. Binding of GHRH leads to the coupling of GHRH-R to G-protein which stimulates increased adenylyl cyclase activity and the accumulation of cAMP leading to the synthesis and release of growth hormone and somatotroph proliferation. In addition, this signalling pathway may have direct action in fetal/placental development, reproduction and immune function. GHRH and GHRH-R may also play a role in the regulation of non-rapid eye movement sleep (NREMS). The expression of GHRH-R is dependent on the presence of the POU domain factor Pit-1. Mutations in the gene encoding this protein can result in isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, and anterior pituitary hypoplasia (APH).
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-8867R-A488)
Dodávateľ: BIOSS INC
Opis: GHRH-R is a seven transmembrane domain protein that localizes to the somatotroph of the pituitary. GHRH-R plays an important role in growth and acts as a high-affinity receptor for GHRH. Binding of GHRH leads to the coupling of GHRH-R to G-protein which stimulates increased adenylyl cyclase activity and the accumulation of cAMP leading to the synthesis and release of growth hormone and somatotroph proliferation. In addition, this signalling pathway may have direct action in fetal/placental development, reproduction and immune function. GHRH and GHRH-R may also play a role in the regulation of non-rapid eye movement sleep (NREMS). The expression of GHRH-R is dependent on the presence of the POU domain factor Pit-1. Mutations in the gene encoding this protein can result in isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, and anterior pituitary hypoplasia (APH).
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-11794R-A350)
Dodávateľ: BIOSS INC
Opis: GHRH-R is a seven transmembrane domain protein that localizes to the somatotroph of the pituitary. GHRH-R plays an important role in growth and acts as a high-affinity receptor for GHRH. Binding of GHRH leads to the coupling of GHRH-R to G-protein which stimulates increased adenylyl cyclase activity and the accumulation of cAMP leading to the synthesis and release of growth hormone and somatotroph proliferation. In addition, this signalling pathway may have direct action in fetal/placental development, reproduction and immune function. GHRH and GHRH-R may also play a role in the regulation of non-rapid eye movement sleep (NREMS). The expression of GHRH-R is dependent on the presence of the POU domain factor Pit-1. Mutations in the gene encoding this protein can result in isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, and anterior pituitary hypoplasia (APH).
Merná jednotka: 1 * 100 µl


Katalógové číslo: (PRSI27-318)
Dodávateľ: PROSCI
Opis: N-Oct-3 (POU3F2) is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1) and Oct2 (POU2F2), and the pituitary protein Pit1 (PIT1). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.N-Oct-3 is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176), and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.[supplied by OMIM].
Merná jednotka: 1 * 50 µG


Katalógové číslo: (BSBTPA1506)
Dodávateľ: Boster Bio
Opis: Rabbit IgG polyclonal antibody for POU domain class 2-associating factor 1(POU2AF1) detection. Tested with WB, IHC-P in Mouse; Rat.
Merná jednotka: 1 * 0,1 mg


Katalógové číslo: (PRSI55-446)
Dodávateľ: PROSCI
Opis: This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development.
Merná jednotka: 1 * 400 µl


Katalógové číslo: (PRSI27-625)
Dodávateľ: PROSCI
Opis: POU domain genes encode a family of highly conserved transacting factors that influence the transcriptional activity of several cell type-specific and ubiquitous genes.
Merná jednotka: 1 * 50 µG


Katalógové číslo: (PRSI77-024)
Dodávateľ: PROSCI
Opis: The EM92 monoclonal antibody reacts with human and mouse Oct 3/4, a POU family transcription factor. Oct 3/4 is encoded by the Pou5F1 gene and expressed on undifferentiated cells and lost in adult tissue. Fbx15, FGF-4, NANOG, Rex1, and UTF1 expression is regulated with Oct 3/4 and in many cases gene expression is regulated in concert with Sox2.
Merná jednotka: 1 * 0,1 mg


Katalógové číslo: (PRSI28-073)
Dodávateľ: PROSCI
Opis: POU2F2 is a member of the POU family and is predominantly expressed in B cells, in activated T cells, and in the nervous system.
Merná jednotka: 1 * 100 µG


Dodávateľ: MRAZ EDWIN
Opis: PP, coloured with lip seal.

Katalógové číslo: (PRSI31-205)
Dodávateľ: PROSCI
Opis: N-Oct-3 (POU3F2) is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1) and Oct2 (POU2F2), and the pituitary protein Pit1 (PIT1). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression. N-Oct-3 is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176), and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.[supplied by OMIM].
Merná jednotka: 1 * 50 µG


Katalógové číslo: (USBI145557)
Dodávateľ: UNITED BIOCHEMICALS
Opis: Anti-Oct-4A Mouse Monoclonal Antibody NL®)493 [clone: 653108]
Merná jednotka: 1 * 500 µl


Katalógové číslo: (PRSI33-464)
Dodávateľ: PROSCI
Opis: Transcription factor that seems to function synergistically with the POU domain protein TST-1/OCT6/SCIP. Could confer cell specificity to the function of other transcription factors in developing and mature glia (By similarity). [UniProt].
Merná jednotka: 1 * 100 µG


Katalógové číslo: (USBI145558)
Dodávateľ: UNITED BIOCHEMICALS
Opis: Anti-Oct-4A Mouse Monoclonal Antibody NL®)557 [clone: 653108]
Merná jednotka: 1 * 500 µl


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