Hľadali ste: Ethyl+2-(4-(trifluoromethy)phenoxy)acetoacetate

Katalógové číslo: (BOSSBS-5089R-CY5.5)

Dodávateľ: BIOSS INC

Opis: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-5089R-CY7)

Dodávateľ: BIOSS INC

Opis: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-11383R-FITC)

Dodávateľ: BIOSS INC

Opis: ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family. Encoded by a gene that maps to human chromosome 12q24.31, ACSF1 is highly expressed in kidney, heart and brain, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). Existing as three alternatively spliced isoforms, ACSF1 participates in ATP binding, ligase activity, acetoacetate-CoA ligase activity and nucleotide binding. The ACSF1 promoter is a known PPAR?target gene, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1). ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-11383R-A750)

Dodávateľ: BIOSS INC

Opis: ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family. Encoded by a gene that maps to human chromosome 12q24.31, ACSF1 is highly expressed in kidney, heart and brain, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). Existing as three alternatively spliced isoforms, ACSF1 participates in ATP binding, ligase activity, acetoacetate-CoA ligase activity and nucleotide binding. The ACSF1 promoter is a known PPAR target gene, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1). ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-5041R-A555)

Dodávateľ: BIOSS INC

Opis: This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-5041R-A750)

Dodávateľ: BIOSS INC

Opis: This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyses the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-15472R-A488)

Dodávateľ: BIOSS INC

Opis: HGD is a 445 amino acid protein that belongs to the homogentisate dioxygenase family and is involved in the pathway of amino acid degradation. Expressed at high levels in kidney, colon, liver, prostate and small intestine, HGD uses iron as a cofactor to catalyse the oxygen-dependent conversion of homogentisate to 4-maleylacetoacetate, a reaction that is the fourth step in the creation of L-phenylalanine from fumarate and acetoacetic acid. Defects in the gene encoding HGD are the cause of alkaptonuria (AKU), an autosomal recessive disorder that is characterised by urine that turns dark on standing and alkalinisation, black ochronotic pigmentation of cartilage and collagenous tissues and spine arthritis.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-15472R-A647)

Dodávateľ: BIOSS INC

Opis: HGD is a 445 amino acid protein that belongs to the homogentisate dioxygenase family and is involved in the pathway of amino acid degradation. Expressed at high levels in kidney, colon, liver, prostate and small intestine, HGD uses iron as a cofactor to catalyse the oxygen-dependent conversion of homogentisate to 4-maleylacetoacetate, a reaction that is the fourth step in the creation of L-phenylalanine from fumarate and acetoacetic acid. Defects in the gene encoding HGD are the cause of alkaptonuria (AKU), an autosomal recessive disorder that is characterised by urine that turns dark on standing and alkalinisation, black ochronotic pigmentation of cartilage and collagenous tissues and spine arthritis.

Merná jednotka: 1 * 100 µl

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Dodávateľ: Apollo Scientific

Opis: 3-(Trifluoromethyl)picolinic acid 97%

Katalógové číslo: (BOSSBS-2698R-A647)

Dodávateľ: BIOSS INC

Opis: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-15589R-CY3)

Dodávateľ: BIOSS INC

Opis: OXCT2 is a testis-specific succinyl-CoA:3-oxoacid CoA transferase (EC 2,8,3,5), which catalyses the reversible transfer of CoA from succinyl-CoA to acetoacetate in the first step of ketone body utilisation. See also OXCT1 (MIM 601424).

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-15589R-FITC)

Dodávateľ: BIOSS INC

Opis: OXCT2 is a testis-specific succinyl-CoA:3-oxoacid CoA transferase (EC 2,8,3,5), which catalyses the reversible transfer of CoA from succinyl-CoA to acetoacetate in the first step of ketone body utilisation. See also OXCT1 (MIM 601424).

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-5089R-A647)

Dodávateľ: BIOSS INC

Opis: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

Merná jednotka: 1 * 100 µl

Predaj

Katalógové číslo: (BOSSBS-5089R-FITC)

Dodávateľ: BIOSS INC

Opis: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

Merná jednotka: 1 * 100 µl

Predaj

Katalógové číslo: (BOSSBS-2698R-CY7)

Dodávateľ: BIOSS INC

Opis: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).

Merná jednotka: 1 * 100 µl

Predaj

Katalógové číslo: (BOSSBS-15472R-CY7)

Dodávateľ: BIOSS INC

Opis: HGD is a 445 amino acid protein that belongs to the homogentisate dioxygenase family and is involved in the pathway of amino acid degradation. Expressed at high levels in kidney, colon, liver, prostate and small intestine, HGD uses iron as a cofactor to catalyse the oxygen-dependent conversion of homogentisate to 4-maleylacetoacetate, a reaction that is the fourth step in the creation of L-phenylalanine from fumarate and acetoacetic acid. Defects in the gene encoding HGD are the cause of alkaptonuria (AKU), an autosomal recessive disorder that is characterised by urine that turns dark on standing and alkalinisation, black ochronotic pigmentation of cartilage and collagenous tissues and spine arthritis.

Merná jednotka: 1 * 100 µl

Predaj