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Product Image-20-1172-U100

Anti-KIT Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: ACK2]

Dodávateľ: TONBO BIOSCIENCE
Opis: The ACK2 antibody is specific for CD117, also called c-Kit, a 145 kDa cytokine receptor important in the development of hematopoietic stem cells, in oogenesis, and for functional activity of immune cells such as NK and mast cells. c-Kit binds to a ligand known as stem cell factor (SCF), or alternatively as mast cell growth factor. Ligand binding promotes the activation (dimerization) and subsequent tyrosine kinase activity of the c-Kit receptor and triggers key survival, expansion and maturation signals during hematopoietic progenitor cell development. Conversely, shedding of extracellular domain of c-Kit receptor is reported to induce inactivation or apoptosis within these cells. The survival signaling activity of c-Kit confers a proto-oncogenic attribute to the receptor, as overexpression or mutations in this protein are associated with tumor development.

KBÚ – slovenskú verziu si vyžiadajte na regulatory.cz@avatorsciences.com

Image Unavailable-ENZOBMLKI1410030

Reagents for Color-de-Lys™ HDAC colorimetric activity assay kit

Dodávateľ: ENZO LIFE SCIENCES
Opis: Cellular assay, Color-de-Lys™ developer concentrate, 300 µl

Product Image-28-9505-13

Cation exchange chromatography column, HiScreen™ SP FF

Katalógové číslo: (28-9505-13)
Dodávateľ: Cytiva
Opis: HiScreen SP FF columns are prepacked with SP Sepharose Fast Flow, a strong cation exchanger, and are part of the process development platform available from Cytiva. The columns are an excellent choice for method optimization and parameter screening.
Merná jednotka: 1 * 1 items

KBÚ – slovenskú verziu si vyžiadajte na regulatory.cz@avatorsciences.com


Product Image-786-20LATEX

Protein Assay, Protn-Latex™

Katalógové číslo: (786-20LATEX)
Dodávateľ: G BIOSCIENCES
Opis: A simple and reliable method for estimation of protein contamination in latex. Detects as low as 25 to 40 μg protein/gm latex (or 25 to 50 ppm). Protein solutions applied to the test strips form compact and symmetrical spots, their diameter being directly proportional to protein concentration. Protn-Latex™ latex protein extraction buffer extracts protein from the latex sample, which is then applied to the test strips and rapidly developed. By measuring the Ø of protein spots with the Protn-Latex™ card, the range of protein concentration in the sample can be determined.
Merná jednotka: 1 * 1 KIT
Image Unavailable-60-1172-U100

Anti-CD117 (c-Kit) Rat Monoclonal Antibody (PE (Phycoerythrin)-Cy7) [clone: ACK2]

Dodávateľ: TONBO BIOSCIENCE
Opis: The ACK2 antibody is specific for CD117, also called c-Kit, a 145 kDa cytokine receptor important in the development of hematopoietic stem cells, in oogenesis, and for functional activity of immune cells such as NK and mast cells. c-Kit binds to a ligand known as stem cell factor (SCF), or alternatively as mast cell growth factor. Ligand binding promotes the activation (dimerisation) and subsequent tyrosine kinase activity of the c-Kit receptor and triggers key survival, expansion and maturation signals during hematopoietic progenitor cell development. Conversely, shedding of extracellular domain of c-Kit receptor is reported to induce inactivation or apoptosis within these cells. The survival signaling activity of c-Kit confers a proto-oncogenic attribute to the receptor, as overexpression or mutations in this protein are associated with tumor development.

Product Image-28-9269-79

Cation exchange chromatography column, HiScreen™ Capto™ S

Katalógové číslo: (28-9269-79)
Dodávateľ: Cytiva
Opis: HiScreen Capto S columns are prepacked with Capto S ion exchange chromatography medium, and are part of the process development platform available from Cytiva. The columns are an excellent choice for method optimization and parameter screening.
Merná jednotka: 1 * 1 items
Product Image-HEWL959764-902

HPLC columns, ZORBAX® Eclipse Plus

Dodávateľ: AGILENT HEWLETT PACKARD
Opis: Eclipse Plus columns are recommended for initial method development from pH 2 to 9 and provide high resolution and excellent peak shape of all types of compounds.

Image Unavailable-ENZOBMLKI1770005

Fluor-de-Lys® SIRT1 deacetylase substrate

Katalógové číslo: (ENZOBMLKI1770005)
Dodávateľ: ENZO LIFE SCIENCES
Opis: Fluor de Lys®-SIRT1 is a fluorogenic, acetylated peptide substrate for SIRT1 (human Sirtuin 1). Based on residues 379-382 of p53 (Arg-His-Lys-Lys(Ac)), a site of regulatory acetylation by the p300 and CBP acetyltransferases (lysines 381, 382), it was the best substrate for SIRT1 from among a panel of substrates patterned on p53, histone H3, and histone H4 acetylation sites. Fluor de Lys®-SIRT1 is deacetylated by SIRT1 (BML-SE239) at a rate of more then 8-fold that of the acetylated lysine substrate, Fluor de Lys® (Prod. No. BML-KI104; acetylated substrates both at 25 µM, 500 µM NAD+). The Km of Fluor de Lys®-SIRT1 for human recombinant Sirtuin 1 is 108 µM (determined at 37°C, 500 µM NAD+). Must be used in conjunction with Fluor de Lys® Developer II (Prod. No. BML-KI176). Fluorescent signal indicates deacetylation of Lys382. Sufficient for 100-200 assays of human recombinant SIRT1 (1U/well, 50-100 µM substrate).
Merná jednotka: 1 * 1 Vial
Product Image-JSPABPT080-000-000

Qualitative fit testing kit, JSP LTD

Dodávateľ: JSP
Opis: Dust and half masks commonly fail to do the job they are intended to do because of poor fitting and care by the user. Qualitative Fit Testing can be used not only as a test method to ensure wearers are properly protected, but also as a very effective way of training them in the correct way of fitting a mask.

Image Unavailable-30127.

ExoBrite™ EV Surface Stain Sampler Kit

Katalógové číslo: (30127.)
Dodávateľ: BIOTIUM
Opis: The ExoBrite™ EV Surface Stain Sampler Kit, Green was developed to offer each of Biotium’s ExoBrite™ EV Surface Stains (CTB, WGA, and Annexin V) for assessing which stain offers the best coverage for the EV samples of interest.
Merná jednotka: 1 * 1 Each
Product Image-28-9269-77

Protein A column, HiScreen™ MabSelect SuRe™

Katalógové číslo: (28-9269-77)
Dodávateľ: Cytiva
Opis: The HiScreen MabSelect SuRe column uses protein A chromatography for antibody purification. This protein A column is prepacked with MabSelect SuRe affinity resin and is part of our process development platform. These packed columns are used for method optimization and parameter screening for capture of monoclonal antibodies.
Merná jednotka: 1 * 1 items
Product Image-28-9269-80

Ion exchange chromatography column, HiScreen™ Capto™ MMC

Katalógové číslo: (28-9269-80)
Dodávateľ: Cytiva
Opis: HiScreen Capto MMC columns are prepacked with Capto MMC ion exchange chromatography medium, and are part of the process development platform available from Cytiva. The columns are an excellent choice for method optimization and parameter screening.
Merná jednotka: 1 * 1 items
Image Unavailable-ENZOBMLAK5180001

FLUOR DE LYS® HDAC8 fluorometric drug discovery kit

Katalógové číslo: (ENZOBMLAK5180001)
Dodávateľ: ENZO LIFE SCIENCES
Opis: A Fluor-de-Lys® fluorescent assay system. The HDAC8 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human HDAC8 included in the kit. The kit is ideal for chemical library screening for candidate inhibitors or activators or kinetic assay of the enzyme under varying conditions. The Fluor de Lys® HDAC8 assay is based on the Fluor de Lys® Substrate and Fluor de Lys® Developer combination. The assay procedure has two steps. First, the Fluor de Lys® Substrate, which comprises an acetylated lysine side chain, is incubated with HDAC6. Deacetylation of the substrate sensitizes the substrate so that, in the second step, treatment with the Fluor de Lys®Developer produces a fluorophore.
Merná jednotka: 1 * 1 KIT
Product Image-17-5474-15

Affinity chromatography column, HiScreen™ MabSelect SuRe™ LX

Katalógové číslo: (17-5474-15)
Dodávateľ: Cytiva
Opis: This protein A column is prepacked with MabSelect SuRe LX affinity resin and is part of our process development platform. These packed columns are an excellent choice for method optimization and parameter screening for capture of monoclonal antibodies when a high dynamic binding capacity is needed.
Merná jednotka: 1 * 1 items
Product Image-TOYO0045377

SkillPak™ BIO Pre-Packed Columns

Dodávateľ: TOSOH BIOSCIENCE
Opis: SkillPak™ BIO pre-packed columns are designed for a fast method development and scale-up of multi-column chromatography (MCC) or continuous chromatography processes. They are pre-packed with TOYOPEARL® process chromatography media for bioseparations.

Product Image-28-9269-81

Ion exchange chromatography column, HiScreen™ Capto™ adhere

Katalógové číslo: (28-9269-81)
Dodávateľ: Cytiva
Opis: HiScreen Capto adhere columns are prepacked with Capto adhere ion exchange chromatography resins, and are part of the process development platform available from Cytiva. The columns are an excellent choice for method optimization and parameter screening.
Merná jednotka: 1 * 1 items
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