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Image Unavailable-BOSSBS-9207R

Anti-GDPD5 Rabbit Polyclonal Antibody

Katalógové číslo: (BOSSBS-9207R)
Dodávateľ: BIOSS INC
Opis: Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7836R-CY3

Anti-DCTN2 Rabbit Polyclonal Antibody (Cy3®)

Katalógové číslo: (BOSSBS-7836R-CY3)
Dodávateľ: BIOSS INC
Opis: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6090R-CY3

Anti-RBM5 Rabbit Polyclonal Antibody (Cy3®)

Katalógové číslo: (BOSSBS-6090R-CY3)
Dodávateľ: BIOSS INC
Opis: RBM5 (RNA binding motif protein 5) is a nuclear SR related RNA binding protein which specifically binds poly(G) RNA homopolymers in vitro. It modulates both apoptosis and the cell cycle, and retards tumor formation.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-0985R-CY3

Anti-MMP20 Rabbit Polyclonal Antibody (Cy3®)

Katalógové číslo: (BOSSBS-0985R-CY3)
Dodávateľ: BIOSS INC
Opis: Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6473R-A680

Anti-MUSK Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalógové číslo: (BOSSBS-6473R-A680)
Dodávateľ: BIOSS INC
Opis: Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle (PubMed:25537362). Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganisation of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane. May regulate AChR phosphorylation and clustering through activation of ABL1 and Src family kinases which in turn regulate MUSK. DVL1 and PAK1 that form a ternary complex with MUSK are also important for MUSK-dependent regulation of AChR clustering. May positively regulate Rho family GTPases through FNTA. Mediates the phosphorylation of FNTA which promotes prenylation, recruitment to membranes and activation of RAC1 a regulator of the actin cytoskeleton and of gene expression. Other effectors of the MUSK signaling include DNAJA3 which functions downstream of MUSK. May also play a role within the central nervous system by mediating cholinergic responses, synaptic plasticity and memory formation (By similarity).
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7876R-CY7

Anti-SPAG8 Rabbit Polyclonal Antibody (Cy7®)

Katalógové číslo: (BOSSBS-7876R-CY7)
Dodávateľ: BIOSS INC
Opis: May play a role in fertility and microtubule formation through interaction with RANBP9.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-12486R-A647

Anti-CDC16 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalógové číslo: (BOSSBS-12486R-A647)
Dodávateľ: BIOSS INC
Opis: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7778R-A680

Anti-APC5 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalógové číslo: (BOSSBS-7778R-A680)
Dodávateľ: BIOSS INC
Opis: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5786R-CY3

Anti-SERPINA4 Rabbit Polyclonal Antibody (Cy3®)

Katalógové číslo: (BOSSBS-5786R-CY3)
Dodávateľ: BIOSS INC
Opis: Kallistatin is a serine proteinase inhibitor which binds to tissue kallikrein and inhibits its amidolytic and kininogenase activity. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5786R-CY7

Anti-SERPINA4 Rabbit Polyclonal Antibody (Cy7®)

Katalógové číslo: (BOSSBS-5786R-CY7)
Dodávateľ: BIOSS INC
Opis: Kallistatin is a serine proteinase inhibitor which binds to tissue kallikrein and inhibits its amidolytic and kininogenase activity. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6473R-A647

Anti-MUSK Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalógové číslo: (BOSSBS-6473R-A647)
Dodávateľ: BIOSS INC
Opis: Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle (PubMed:25537362). Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane. May regulate AChR phosphorylation and clustering through activation of ABL1 and Src family kinases which in turn regulate MUSK. DVL1 and PAK1 that form a ternary complex with MUSK are also important for MUSK-dependent regulation of AChR clustering. May positively regulate Rho family GTPases through FNTA. Mediates the phosphorylation of FNTA which promotes prenylation, recruitment to membranes and activation of RAC1 a regulator of the actin cytoskeleton and of gene expression. Other effectors of the MUSK signaling include DNAJA3 which functions downstream of MUSK. May also play a role within the central nervous system by mediating cholinergic responses, synaptic plasticity and memory formation (By similarity).
Merná jednotka: 1 * 100 µl
Product Image-590-0218

Label maker, b.safe

Dodávateľ: Bohlender
Opis: Portable label printer with computer-style keyboard, large LCD display and 20 methods to format text.

Image Unavailable-BOSSBS-7778R-A488

Anti-ANAPC5 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalógové číslo: (BOSSBS-7778R-A488)
Dodávateľ: BIOSS INC
Opis: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-0772R-HRP

Anti-FSCN1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalógové číslo: (BOSSBS-0772R-HRP)
Dodávateľ: BIOSS INC
Opis: Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
Merná jednotka: 1 * 100 µl
Image Unavailable-ENZOBMLAK0150001

MMP Inhibitor profiling kit, colorimetric

Katalógové číslo: (ENZOBMLAK0150001)
Dodávateľ: ENZO LIFE SCIENCES
Opis: A QUANTIZYME® Assay System Complete assay system designed to examine the specificity of inhibitors against a panel of ten matrix metalloproteinase enzymes. The assays are performed in a convenient 96-well microplate format using a chromogenic substrate1,2 detected at 412 nm. Included are active MMP enzymes, assay buffer, a prototypic control inhibitor (NNGH3), and a detailed instruction booklet.
Merná jednotka: 1 * 1 KIT
Image Unavailable-BOSSBS-2686R-CY5.5

Anti-DKK3 Rabbit Polyclonal Antibody (Cy5.5®)

Katalógové číslo: (BOSSBS-2686R-CY5.5)
Dodávateľ: BIOSS INC
Opis: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Merná jednotka: 1 * 100 µl
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