Hľadali ste: Tonbo Biosciences

Katalógové číslo: (75-4714-U100)

Dodávateľ: TONBO BIOSCIENCE

Opis: The MOPC-21 immunoglobulin is useful as an isotype-matched control. The MOPC-21 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG1 antibodies.

Merná jednotka: 1 * 100 µG

Predaj

Dodávateľ: TONBO BIOSCIENCE

Opis: The BNI3 antibody is specific for human CD152, commonly known as CTLA-4, a 33 to 37 kDa protein expressed as a homodimer on the surface of activated T and B cells, and on thymocytes. CTLA-4 is structurally similar, yet functionally disparate, to the T cell co-stimulatory molecule CD28. Both CTLA-4 and CD28 interact with the co-stimulatory molecules CD80 (B7-1) and CD86 (B7-2) on antigen-presenting cells, with CTLA-4 displaying a higher avidity than CD28. While CD28 typically delivers a potent co-stimulatory signal in support of T cell activation, CTLA-4 appears to act as a negative regulator of T cell activation and may contribute to the suppressor function of Treg cells.

Katalógové číslo: (30-8055-U500)

Dodávateľ: TONBO BIOSCIENCE

Opis: Goat anti-Mouse IgG (H&L), F(ab')2 Fragment - Affinity Pure, Biotin Conjugate, min x w/human IgG or serum proteins

Merná jednotka: 1 * 0,5 mg

Predaj

Katalógové číslo: (35-8055-U500)

Dodávateľ: TONBO BIOSCIENCE

Opis: Goat anti-Mouse IgG (H&L), F(ab')2 Fragment - Affinity Pure, FITC Conjugate, min x w/human IgG or serum proteins

Merná jednotka: 1 * 0,5 mg

Predaj

Katalógové číslo: (35-8026-M001)

Dodávateľ: TONBO BIOSCIENCE

Opis: Goat anti-Human IgE (epsilon chain) - Affinity Pure, FITC Conjugate

Merná jednotka: 1 * 1 mg

Predaj

Katalógové číslo: (35-8028-M001)

Dodávateľ: TONBO BIOSCIENCE

Opis: Goat anti-Human IgM (mu chain) - Affinity Pure, FITC Conjugate

Merná jednotka: 1 * 1 mg

Predaj

Dodávateľ: TONBO BIOSCIENCE

Opis: The 61D3 antibody is specific for human CD14, a 53 to 55 kDa GPI-anchored glycoprotein. CD14 is highly expressed on monocytes and to a lesser extent on interfollicular macrophages, and some dendritic cells. Together with LPS-Binding Protein (LBP), CD14 binds to and mediates the innate immune response to bacterial lipopolysaccharide (LPS).

Katalógové číslo: (72-8108-U500)

Dodávateľ: TONBO BIOSCIENCE

Opis: Goat anti-Human IgG (H&L), F(ab')2 Fragment - Affinity Pure, HRP Conjugate, min x w/bovine, mouse or rabbit serum proteins

Merná jednotka: 1 * 0,5 mg

Predaj

Katalógové číslo: (72-8113-M001)

Dodávateľ: TONBO BIOSCIENCE

Opis: Rabbit anti-Chicken IgY (H&L) - Affinity Pure, HRP Conjugate

Merná jednotka: 1 * 1 mg

Predaj

Katalógové číslo: (65-4714-U100)

Dodávateľ: TONBO BIOSCIENCE

Opis: PerCP-Cyanine5.5 Mouse IgG1 Isotype Control (MOPC-21)

Merná jednotka: 1 * 100 µG

Predaj

Dodávateľ: TONBO BIOSCIENCE

Opis: The BC96 antibody is specific for human CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, although with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Signaling via CD25 may modulate Th17 and Treg cell differentiation, and has been shown to play a role in the function of dendritic cells.

Katalógové číslo: (70-0116-U100)

Dodávateľ: TONBO BIOSCIENCE

Opis: The 3.9 antibody reacts with human CD11c, also known as integrin alpha X. This 150 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha X (CD11c) assembles with Integrin beta-2 (CD18) into a receptor known as CR4 which can bind and induce signaling through ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.

Merná jednotka: 1 * 100 µG

Predaj

Dodávateľ: TONBO BIOSCIENCE

Opis: The UCHT2 antibody is specific for human CD5, a 67 kD transmembrane glycoprotein, that is expressed on most thymocytes, mature T cells, and a subset of B cells. CD5 is involved in modulating antigen receptor signaling in both T and B cells and binds to CD72, expressed on B cells.

Dodávateľ: TONBO BIOSCIENCE

Opis: The OKT8 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Katalógové číslo: (65-0289-T100)

Dodávateľ: TONBO BIOSCIENCE

Opis: The CD28.2 antibody reacts with human CD28, a 44 kDa type I surface glycoprotein which acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, known as B7-1 (CD80) and B7-2 (CD86), which are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. Other members of the CD28 family of receptors include CTLA-4 (CD152), PD-1 (CD279), ICOS and BTLA.

Merná jednotka: 1 * 100 Tests

Predaj

Katalógové číslo: (75-5921-U100)

Dodávateľ: TONBO BIOSCIENCE

Opis: The TER-119 antibody is named for the antigen to which it binds, a 52 kDa surface protein that is associated with glycophorin-A. TER-119 is considered to be a lineage marker for later stages of erythroid cell development, as its expression begins at the pro-erythroblast stage. TER-119 antigen is not expressed at either BFU-E or CFU-E stages, i.e. prior to the pro-erythroblast stage.

Merná jednotka: 1 * 100 µG

Predaj