Hľadali ste: Tonbo Biosciences

Dodávateľ: TONBO BIOSCIENCE

Opis: The TER-119 antibody is named for the antigen to which it binds, a 52 kDa surface protein that is associated with glycophorin-A. TER-119 is considered to be a lineage marker for later stages of erythroid cell development, as its expression begins at the pro-erythroblast stage. TER-119 antigen is not expressed at either BFU-E or CFU-E stages, i.e. prior to the pro-erythroblast stage.

Dodávateľ: TONBO BIOSCIENCE

Opis: The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte 'rolling' on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.

Dodávateľ: TONBO BIOSCIENCE

Opis: The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.

Katalógové číslo: (92-7770-T100)

Dodávateľ: TONBO BIOSCIENCE

Opis: The FITC Mouse Lineage Cocktail contains a combination of pre-diluted antibodies that identify lineage committed cells by flow cytometry and facilitate their exclusion from hematopoietic progenitor cells in mouse bone marrow. The antibodies in the cocktail react with cells from major hematopoietic lineages including T, B and NK cells, monocytes/macrophages, granulocytes and erythrocytes. The Lineage Cocktail contains the following FITC conjugated antibodies: anti-mouse CD3 (17A2), anti-mouse CD11b (M1/70), anti-mouse CD45/B220 (RA3-6B2), anti-mouse Ly-6G (Gr-1) (RB6-8C5) and anti-mouse TER-119 (TER-119). An Isotype Control Cocktail consisting of FITC conjugated isotype-matched control antibodies (Rat IgG2a, kappa; Rat IgG2b, kappa) is also provided in a separate vial.

Merná jednotka: 1 * 100 Tests

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Katalógové číslo: (70-0458-U100)

Dodávateľ: TONBO BIOSCIENCE

Opis: The HI100 antibody reacts with the human CD45 isoform known as CD45RA, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RB, CD45RO and others.

Merná jednotka: 1 * 100 µG

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Dodávateľ: TONBO BIOSCIENCE

Opis: The 2D1 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, and CD45RO.

Dodávateľ: TONBO BIOSCIENCE

Opis: The MP4-25D2 antibody is specific for human IL-4, a pleiotropic cytokine that Th2 cell differentiation, B cell proliferation and differentiation, and B cell class switching to IgE. MP4-25D2 is a neutralizing antibody and is reported to cross react with rhesus monkey IL-4.

Katalógové číslo: (40-9985-U100)

Dodávateľ: TONBO BIOSCIENCE

Opis: The J43.1 antibody is specific for mouse CD279, also known as programmed death-1 (PD-1), a 55 kDa glycoprotein which can co-regulate T cell antigen receptor signaling and therefore modulate T cell activation. PD-1 exists in a monomeric form that is expressed by CD4- CD8- thymocytes, where it participates in the processes of clonal selection, elimination of autoreactive lymphocytes, and development of tolerance. PD-1 expression is also inducible upon activation of mature T cells, where it has been proposed to interact with the co-stimulatory receptor CD80 to limit T cell activation. Two ligands for PD-1, known as PD-L1 (B7-H1) and PD-L2 (B7-DC) are differentially expressed on T and B cells, monocytes, macrophages, NK cells or dendritic cells. PD-1 is a member of a family of receptors including CD28 and CTLA-4 (CD152), which interact with 'B7' ligands to provide a balance of co-stimulatory /co-inhibitory signaling important in T cell activation, tolerance, and autoimmunity.

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (70-8040-M002)

Dodávateľ: TONBO BIOSCIENCE

Opis: Goat anti-Mouse IgG (H&L) - Affinity Pure, min x w/bovine, horse, human, pig or rabbit serum protein

Merná jednotka: 1 * 2 mg

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Katalógové číslo: (35-8070-M002)

Dodávateľ: TONBO BIOSCIENCE

Opis: Goat anti-Rabbit IgG (H&L) - Affinity Pure, FITC Conjugate, min x w/bovine, human, or mouse IgG

Merná jednotka: 1 * 2 mg

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Katalógové číslo: (70-8076-M002)

Dodávateľ: TONBO BIOSCIENCE

Opis: Rabbit anti-Mouse IgG (H&L) - Affinity Pure

Merná jednotka: 1 * 2 mg

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Katalógové číslo: (50-8035-U100)

Dodávateľ: TONBO BIOSCIENCE

Opis: Goat anti-Mouse IgG2b, secondary antibody, conjugated to SureLight® R-Phycoerythrin

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (35-8058-U500)

Dodávateľ: TONBO BIOSCIENCE

Opis: Goat anti-Rabbit IgG (H&L), F(ab')2 Fragment - Affinity Pure, FITC Conjugate

Merná jednotka: 1 * 0,5 mg

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Katalógové číslo: (72-8081-M001)

Dodávateľ: TONBO BIOSCIENCE

Opis: Goat anti-Chicken IgY (H&L) - Affinity Pure, HRP Conjugate

Merná jednotka: 1 * 1 mg

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Katalógové číslo: (50-8033-U100)

Dodávateľ: TONBO BIOSCIENCE

Opis: Goat anti-mouse IgG (H+L), secondary antibody, SureLight® R-Phycoerythrin, 100ug

Merná jednotka: 1 * 100 µG

Predaj

Katalógové číslo: (35-8067-M002)

Dodávateľ: TONBO BIOSCIENCE

Opis: Goat anti-Rabbit IgG (H&L) - Affinity Pure, FITC Conjugate

Merná jednotka: 1 * 2 mg

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