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Image Unavailable-BOSSBS-3818R-FITC

Anti-GDF15 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalógové číslo: (BOSSBS-3818R-FITC)
Dodávateľ: BIOSS INC
Opis: Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.
Merná jednotka: 1 * 100 µl
Product Image-116-0611

Accessories for Label Printers, BBP11 and BBP12

Katalógové číslo: (116-0611)
Dodávateľ: BRADY
Opis: External material holder, Pro: BBP12
Merná jednotka: 1 * 1 items
Image Unavailable-BOSSBS-1619R-HRP

Anti-Smad1 + Smad5 Rabbit Polyclonal Antibody (HRP (Horseradish PE (Phycoerythrin)rOxidase))

Katalógové číslo: (BOSSBS-1619R-HRP)
Dodávateľ: BIOSS INC
Opis: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
Merná jednotka: 1 * 100 µl
Product Image-705-0712

Portable turbidity meters, Turb® 355

Katalógové číslo: (705-0712)
Dodávateľ: WTW
Opis: The Turb 355 provide the user with the choice to perform nephelometric measurements at 90° scattered light, either with an infrared or tungsten white light source.
Merná jednotka: 1 * 1 items
Product Image-BRDY046134

Portable/wall group lockout box, Prinzing

Katalógové číslo: (BRDY046134)
Dodávateľ: BRADY
Opis: This box accommodates 8 to 10 locks (depending on lock size).
Merná jednotka: 1 * 1 items
Product Image-BRDY176992

Brady® M410 Utility Hook

Katalógové číslo: (BRDY176992)
Dodávateľ: BRADY
Opis: Take your printer wherever you work. Hang it easily on a cart, tool belt, rack or bucket organiser with this durable utility hook. Save space and print right where the work happens.
Merná jednotka: 1 * 1 items
Product Image-BRDY050939

Accessories for lockout boxes, mini

Katalógové číslo: (BRDY050939)
Dodávateľ: BRADY
Opis: Additional key hooks for portable plastic lock box and mini wall lock boxes
Merná jednotka: 1 * 12 items
Product Image-BOSSBS-3582R

Anti-TRIM33 Rabbit Polyclonal Antibody

Katalógové číslo: (BOSSBS-3582R)
Dodávateľ: BIOSS INC
Opis: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1619R-A647

Anti-Smad1 + Smad5 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalógové číslo: (BOSSBS-1619R-A647)
Dodávateľ: BIOSS INC
Opis: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1619R-A750

Anti-Smad1 + Smad5 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalógové číslo: (BOSSBS-1619R-A750)
Dodávateľ: BIOSS INC
Opis: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1778R-A680

Anti-GATA4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalógové číslo: (BOSSBS-1778R-A680)
Dodávateľ: BIOSS INC
Opis: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1778R-A647

Anti-GATA4 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalógové číslo: (BOSSBS-1778R-A647)
Dodávateľ: BIOSS INC
Opis: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3818R-A680

Anti-GDF15/MIC-1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalógové číslo: (BOSSBS-3818R-A680)
Dodávateľ: BIOSS INC
Opis: Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterised by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3860R-A680

Anti-CHRDL2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalógové číslo: (BOSSBS-3860R-A680)
Dodávateľ: BIOSS INC
Opis: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterised as a novel protein exclusively expressed in breast, lung, and colon tumors.
Merná jednotka: 1 * 100 µl
Product Image-BRDY317795

Label Printer, QWERTZ with Bluetooth, M610

Katalógové číslo: (BRDY317795)
Dodávateľ: BRADY
Opis: Get the durability your work demands.
Merná jednotka: 1 * 1 items
Image Unavailable-BOSSBS-3418R-A647

Anti-SMAD1 + SMAD5 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalógové číslo: (BOSSBS-3418R-A647)
Dodávateľ: BIOSS INC
Opis: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
Merná jednotka: 1 * 100 µl
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