Hľadali ste: Bioss

Katalógové číslo: (BOSSBS-0945R)

Dodávateľ: BIOSS INC

Opis: Anti-AFM Rabbit Polyclonal Antibody

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-6874R)

Dodávateľ: BIOSS INC

Opis: Anti-CAT Rabbit Polyclonal Antibody

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-6815R)

Dodávateľ: BIOSS INC

Opis: Anti-LRRC15 Rabbit Polyclonal Antibody

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-1095R)

Dodávateľ: BIOSS INC

Opis: Anti-HCRTR2 Rabbit Polyclonal Antibody

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-1100R)

Dodávateľ: BIOSS INC

Opis: Anti-CD36 Rabbit Polyclonal Antibody

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-3654R)

Dodávateľ: BIOSS INC

Opis: Anti-FPR2 Rabbit Polyclonal Antibody

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-1497R)

Dodávateľ: BIOSS INC

Opis: Anti-MUC1 Rabbit Polyclonal Antibody

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-12862R-A350)

Dodávateľ: BIOSS INC

Opis: The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-12565R-FITC)

Dodávateľ: BIOSS INC

Opis: ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-12862R-A488)

Dodávateľ: BIOSS INC

Opis: The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-12864R-CY3)

Dodávateľ: BIOSS INC

Opis: Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, was originally identified as a growth-promoting factor in the conditioned medium of a mouse pancreatic-cell carcinoma (insulinoma) cell line and has since been identified in humans. BTC is synthesized as a large transmembrane precursor molecule that can be cleaved proteolytically to release the soluble form of BTC or function as membrane-anchored growth factors in juxtacrine signaling. BTC, in addition to stimulating homodimers of ErbB-1 and ErbB-4, is capable of binding and activating all possible combinations of heterodimeric ErbB receptors including the oncogenic ErbB-2/ErbB-3 complex. BTC is also expressed in some human malignancies and may have an important role in tumor growth progression.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-12862R-FITC)

Dodávateľ: BIOSS INC

Opis: The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-9557R-A350)

Dodávateľ: BIOSS INC

Opis: The GLTP (glycolipid transfer protein) superfamily is defined by a unique lipid transfer/binding fold (GLTP fold) that accelerate glycolipid intermembrane transfer. GLTPD2 is a 291 amino acid protein that belongs to the GLTP family. The gene encoding GLTPD2 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth are both linked to mutations on chromosome 17. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-9499R-HRP)

Dodávateľ: BIOSS INC

Opis: Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf62 gene product has been provisionally designated C6orf62 pending further characterization.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-9557R-A647)

Dodávateľ: BIOSS INC

Opis: The GLTP (glycolipid transfer protein) superfamily is defined by a unique lipid transfer/binding fold (GLTP fold) that accelerate glycolipid intermembrane transfer. GLTPD2 is a 291 amino acid protein that belongs to the GLTP family. The gene encoding GLTPD2 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth are both linked to mutations on chromosome 17. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-9560R-A555)

Dodávateľ: BIOSS INC

Opis: KRCC1 is a 259 amino acid protein that is encoded by a gene located on human chromosome 2p11.2. Consisting of 237 million bases, chromosome 2 is the second largest human chromosome and encodes over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstré°‰ syndrome, is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

Merná jednotka: 1 * 100 µl

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