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Image Unavailable-BOSSBS-10381R-FITC

Anti-SMAD1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Opis: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
Katalógové číslo: BOSSBS-10381R-FITC
Merná jednotka: 1 * 100 µl
Dodávateľ: BIOSS INC
Image Unavailable-BOSSBS-10381R-A350

Anti-SMAD1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Opis: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
Katalógové číslo: BOSSBS-10381R-A350
Merná jednotka: 1 * 100 µl
Dodávateľ: BIOSS INC
Image Unavailable-BOSSBS-3418R-HRP

Anti-SMAD1 + SMAD5 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Opis: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
Katalógové číslo: BOSSBS-3418R-HRP
Merná jednotka: 1 * 100 µl
Dodávateľ: BIOSS INC
Product Image-BRDY176432

Multicolor and Cut, Sign and Label Printers, S3700

Opis: Color your way to an improved workplace with the S3700 Sign and Label Printer. With multicolor print and shape cutting capabilities, this printer creates impactful identification that fits your application and workspace needs.
Katalógové číslo: BRDY176432
Merná jednotka: 1 * 1 items
Dodávateľ: BRADY
Product Image-BRDY317798

Label Printer, QWERTY EU with Bluetooth, M610

Opis: Get the durability your work demands.
Katalógové číslo: BRDY317798
Merná jednotka: 1 * 1 items
Dodávateľ: BRADY
Product Image-116-0611

Accessories for Label Printers, BBP11 and BBP12

Opis: External material holder, Pro: BBP12
Katalógové číslo: 116-0611
Merná jednotka: 1 * 1 items
Dodávateľ: BRADY
Product Image-BRDY321983

Accessories for Magicard™ 300 Printers

Opis: Replacement print head unit
Katalógové číslo: BRDY321983
Merná jednotka: 1 * 1 KIT
Dodávateľ: BRADY

New Product


Image Unavailable-BOSSBS-3818R-CY5.5

Anti-GDF15 Rabbit Polyclonal Antibody (Cy5.5®)

Opis: Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.
Katalógové číslo: BOSSBS-3818R-CY5.5
Merná jednotka: 1 * 100 µl
Dodávateľ: BIOSS INC
Image Unavailable-BOSSBS-3818R-FITC

Anti-GDF15 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Opis: Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.
Katalógové číslo: BOSSBS-3818R-FITC
Merná jednotka: 1 * 100 µl
Dodávateľ: BIOSS INC
Image Unavailable-611-5844

Accessories for Compact Dot Matrix Printer

Opis: Printer paper for YDP50, 57×50 mm, 1 kg, W×D×H: 120×315×70 mm
Katalógové číslo: 611-5844
Merná jednotka: 1 * 1 items
Dodávateľ: Sartorius Balances

New Product


Product Image-BRDY176501

Printer Accessories for Models M511 and M211

Opis: Accessories for Brady Printer Models M511 and M211.
Katalógové číslo: BRDY176501
Merná jednotka: 1 * 1 items
Dodávateľ: BRADY
Image Unavailable-BOSSBS-1619R

Anti-Smad1 + Smad5 Rabbit Polyclonal Antibody

Opis: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
Katalógové číslo: BOSSBS-1619R
Merná jednotka: 1 * 100 µl
Dodávateľ: BIOSS INC
Product Image-135-1078

Accessories for biological safety cabinets

Opis: Organic carbon filter, 7,7 kg, Pro: FilterMate™ portable exhausters
Katalógové číslo: 135-1078
Merná jednotka: 1 * 1 items
Dodávateľ: LABCONCO
Image Unavailable-BOSSBS-3582R-CY3

Anti-T1 gamma Rabbit Polyclonal Antibody (Cy3®)

Opis: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
Katalógové číslo: BOSSBS-3582R-CY3
Merná jednotka: 1 * 100 µl
Dodávateľ: BIOSS INC
Image Unavailable-BOSSBS-3582R-CY5

Anti-T1 gamma Rabbit Polyclonal Antibody (Cy5®)

Opis: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
Katalógové číslo: BOSSBS-3582R-CY5
Merná jednotka: 1 * 100 µl
Dodávateľ: BIOSS INC
Image Unavailable-BOSSBS-3582R-CY5.5

Anti-T1 gamma Rabbit Polyclonal Antibody (Cy5.5®)

Opis: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
Katalógové číslo: BOSSBS-3582R-CY5.5
Merná jednotka: 1 * 100 µl
Dodávateľ: BIOSS INC
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