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Image Unavailable-BOSSBS-9114R-CY3

Anti-BAGE2 Rabbit Polyclonal Antibody (Cy3®)

Katalógové číslo: (BOSSBS-9114R-CY3)
Dodávateľ: BIOSS INC
Opis: Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7930R-A555

Anti-PPM1G Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalógové číslo: (BOSSBS-7930R-A555)
Dodávateľ: BIOSS INC
Opis: Tissue specificity:Widely expressed. Most abundant in testis, skeletal muscle, and heart.
Merná jednotka: 1 * 100 µl

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Image Unavailable-BOSSBS-9115R-CY7

Anti-BAGE3 Rabbit Polyclonal Antibody (Cy7®)

Katalógové číslo: (BOSSBS-9115R-CY7)
Dodávateľ: BIOSS INC
Opis: Unknown. Candidate gene encoding tumor antigens.Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7930R-HRP

Anti-PPM1G Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalógové číslo: (BOSSBS-7930R-HRP)
Dodávateľ: BIOSS INC
Opis: Tissue specificity:Widely expressed. Most abundant in testis, skeletal muscle, and heart.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9625R-A350

Anti-NPAP1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalógové číslo: (BOSSBS-9625R-A350)
Dodávateľ: BIOSS INC
Opis: C15orf2 may be involved in spermatogenesis. Testis-specific in adults.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7776R-A488

Anti-UCHL5IP Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalógové číslo: (BOSSBS-7776R-A488)
Dodávateľ: BIOSS INC
Opis: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.Tissue specificity:Detected in spleen, thymus, testis, ovary, small intestine and colon, with highest levels of expression in testis and ovary.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13594R-A680

Anti-DZIP1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalógové číslo: (BOSSBS-13594R-A680)
Dodávateľ: BIOSS INC
Opis: DZIP1 (DAZ interacting protein 1) is also known as DZIP or DZIP2 and is a 867 amino acid protein which is expressed as three isoforms, designated DZIPb, DZIPt1 and DZIPt2. DZIP1 is localized to testis, oocytes, ovary and fetal brain, as well as in embryonic stem cells and germ cells. In testis, DZIP1 is localized to the nucleus and also shows some cytoplasmic distribution in spermatogonia. DZIP1 belongs to the C2H2-type zinc-finger protein family, and, characteristc of the C2H2-type zinc-finger protein family, DZIP1 contains one C2H2-type zinc-finger region through which it is thought to interact with DAZ, an interaction that promotes spermiogenesis. DZIP1 expression is not found in those afflicted with Sertoli cell-only syndrome (characterized by the absence of germ cells in the testis), suggesting that the lack of DZIP1 may be involved in the pathogenesis of Sertoli cell-only syndrome-induced male sterility.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13594R-A350

Anti-DZIP1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalógové číslo: (BOSSBS-13594R-A350)
Dodávateľ: BIOSS INC
Opis: DZIP1 (DAZ interacting protein 1) is also known as DZIP or DZIP2 and is a 867 amino acid protein which is expressed as three isoforms, designated DZIPb, DZIPt1 and DZIPt2. DZIP1 is localized to testis, oocytes, ovary and fetal brain, as well as in embryonic stem cells and germ cells. In testis, DZIP1 is localized to the nucleus and also shows some cytoplasmic distribution in spermatogonia. DZIP1 belongs to the C2H2-type zinc-finger protein family, and, characteristc of the C2H2-type zinc-finger protein family, DZIP1 contains one C2H2-type zinc-finger region through which it is thought to interact with DAZ, an interaction that promotes spermiogenesis. DZIP1 expression is not found in those afflicted with Sertoli cell-only syndrome (characterized by the absence of germ cells in the testis), suggesting that the lack of DZIP1 may be involved in the pathogenesis of Sertoli cell-only syndrome-induced male sterility.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13594R-A647

Anti-DZIP1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalógové číslo: (BOSSBS-13594R-A647)
Dodávateľ: BIOSS INC
Opis: DZIP1 (DAZ interacting protein 1) is also known as DZIP or DZIP2 and is a 867 amino acid protein which is expressed as three isoforms, designated DZIPb, DZIPt1 and DZIPt2. DZIP1 is localized to testis, oocytes, ovary and fetal brain, as well as in embryonic stem cells and germ cells. In testis, DZIP1 is localized to the nucleus and also shows some cytoplasmic distribution in spermatogonia. DZIP1 belongs to the C2H2-type zinc-finger protein family, and, characteristc of the C2H2-type zinc-finger protein family, DZIP1 contains one C2H2-type zinc-finger region through which it is thought to interact with DAZ, an interaction that promotes spermiogenesis. DZIP1 expression is not found in those afflicted with Sertoli cell-only syndrome (characterized by the absence of germ cells in the testis), suggesting that the lack of DZIP1 may be involved in the pathogenesis of Sertoli cell-only syndrome-induced male sterility.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7776R-FITC

Anti-UCHL5IP Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalógové číslo: (BOSSBS-7776R-FITC)
Dodávateľ: BIOSS INC
Opis: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.Tissue specificity:Detected in spleen, thymus, testis, ovary, small intestine and colon, with highest levels of expression in testis and ovary.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13594R-CY5

Anti-DZIP1 Rabbit Polyclonal Antibody (Cy5®)

Katalógové číslo: (BOSSBS-13594R-CY5)
Dodávateľ: BIOSS INC
Opis: DZIP1 (DAZ interacting protein 1) is also known as DZIP or DZIP2 and is a 867 amino acid protein which is expressed as three isoforms, designated DZIPb, DZIPt1 and DZIPt2. DZIP1 is localized to testis, oocytes, ovary and fetal brain, as well as in embryonic stem cells and germ cells. In testis, DZIP1 is localized to the nucleus and also shows some cytoplasmic distribution in spermatogonia. DZIP1 belongs to the C2H2-type zinc-finger protein family, and, characteristc of the C2H2-type zinc-finger protein family, DZIP1 contains one C2H2-type zinc-finger region through which it is thought to interact with DAZ, an interaction that promotes spermiogenesis. DZIP1 expression is not found in those afflicted with Sertoli cell-only syndrome (characterized by the absence of germ cells in the testis), suggesting that the lack of DZIP1 may be involved in the pathogenesis of Sertoli cell-only syndrome-induced male sterility.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6746R-A750

Anti-Cancer testis antigen 65 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalógové číslo: (BOSSBS-6746R-A750)
Dodávateľ: BIOSS INC
Opis: TULP2 is a member of a family of tubby-like (TULP) proteins which share a conserved C terminal region of approximately 200 amino acid residues. It is strongly expressed in testis and is expressed in the retina. It is also expressed in cancer cell lines.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6746R-A680

Anti-Cancer testis antigen 65 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalógové číslo: (BOSSBS-6746R-A680)
Dodávateľ: BIOSS INC
Opis: TULP2 is a member of a family of tubby-like (TULP) proteins which share a conserved C terminal region of approximately 200 amino acid residues. It is strongly expressed in testis and is expressed in the retina. It is also expressed in cancer cell lines.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9719R-A350

Anti-PDE4A8 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalógové číslo: (BOSSBS-9719R-A350)
Dodávateľ: BIOSS INC
Opis: The PDE4A8 is a testis germ cell-specific PDE4A variant. There are two PDE4A variants identified in rat testis (PDE4A8 and an un-characterized 76 kDa PDE4A protein). Spermatogenesis is accompanied by expression of a varied repertoire of PDE4 enzymes at different stages of cell differentiation that presumably perform specialized functions. Confocal microscopic examination revealed the presence of PDE4A8 in primary and secondary spermatids but not in mature spermatozoa. PDE4A8 inhibition results in increased apoptosis of the germ cells accompanied with reduction in the number of mature spermatozoa.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-15401R-A647

Anti-H2BFWT Rabbit Polyclonal Antibody (ALEXA FLUOR® 647)

Katalógové číslo: (BOSSBS-15401R-A647)
Dodávateľ: BIOSS INC
Opis: H2BFWT (H2B histone family member W testis-specific) is a 175 amino acid nuclear membrane histone that belongs to the histone H2B family. In contrast to most H2B histones, H2BFWT does not contain the conserved C-terminal residue involved in monoubiquitination, but is structurally indistinguishable from conventional H2B histones. Also varying from other H2B histones, H2BFWT does not participate in the recruitment of chromosome condensation factors or in the assembly of mitotic chromsomes. Expressed in testis, H2BFWT is present in sperm cells and may be essential to telomere function.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11558R-HRP

Anti-GCNF Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalógové číslo: (BOSSBS-11558R-HRP)
Dodávateľ: BIOSS INC
Opis: Germ cell nuclear factor (GCNF) is an orphan member of the nuclear receptor gene superfamily that influences neurogenesis and germ cell development. GCNF can homodimerize and bind DNA. GCNF regulates paracrine interaction between the oocyte and somatic cells by regulating the expression of BMP-15 and GDF-9, to affect female fertility. GCNF is present in spermatocytes and round spermatids of adult male mouse testis; northern blot and ribonuclease protection assays have shown GCNF is predominant in the testis. The gene expresses three alternatively spliced transcript variants.
Merná jednotka: 1 * 100 µl
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