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Product Image-141-1609

SlimLine PLW 7111 Laboratory Glasswashers

Dodávateľ: MIELE
Opis: The PLW 7111 SlimLine laboratory washers offer a comprehensive and systematic solution for analytically pure reprocessing of laboratory glassware.

Image Unavailable-BOSSBS-9491R-CY3

Anti-INIP Rabbit Polyclonal Antibody (Cy3®)

Katalógové číslo: (BOSSBS-9491R-CY3)
Dodávateľ: BIOSS INC
Opis: The SOSS (Sensor of single-strand DNA) complex consists of multiple proteins that promote DNA repair and G2/M checkpoint downstream of the MRN (Mre11, Rad50 and Nbs1) complex. The complex is composed of SSBP1, INTS3 and C9orf80. Specifically, the SOSS complex binds to ssDNA at DNA lesions that influences diverse endpoints in the cellular DNA damage response. The complex is required for efficient homologous recombination-dependent repair of double-stranded breaks and ATM-dependent signaling pathways. C9orf80, also known as SOSS complex subunit C and Single-stranded DNA-binding protein-interacting protein 1 (SSBIP1), is a 104 amino acid nuclear protein that is a component of the SOSS complex. Upon DNA damage, C9orf80 along with other components of the SOSS complex migrate to the nucleus. There are two isoforms of C9orf80 that are produced as a result of alternative splicing events.
Merná jednotka: 1 * 100 µl

Nové řešení transparentnosti pro evropské zákazníky

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Image Unavailable-BOSSBS-9491R-CY7

Anti-INIP Rabbit Polyclonal Antibody (Cy7®)

Katalógové číslo: (BOSSBS-9491R-CY7)
Dodávateľ: BIOSS INC
Opis: The SOSS (Sensor of single-strand DNA) complex consists of multiple proteins that promote DNA repair and G2/M checkpoint downstream of the MRN (Mre11, Rad50 and Nbs1) complex. The complex is composed of SSBP1, INTS3 and C9orf80. Specifically, the SOSS complex binds to ssDNA at DNA lesions that influences diverse endpoints in the cellular DNA damage response. The complex is required for efficient homologous recombination-dependent repair of double-stranded breaks and ATM-dependent signaling pathways. C9orf80, also known as SOSS complex subunit C and Single-stranded DNA-binding protein-interacting protein 1 (SSBIP1), is a 104 amino acid nuclear protein that is a component of the SOSS complex. Upon DNA damage, C9orf80 along with other components of the SOSS complex migrate to the nucleus. There are two isoforms of C9orf80 that are produced as a result of alternative splicing events.
Merná jednotka: 1 * 100 µl
Product Image-TEST0563.0004.10

Heating kit, smart probes

Katalógové číslo: (TEST0563.0004.10)
Dodávateľ: TESTO
Opis: Compact kit containing three measuring instruments for carrying out your most important measuring tasks involving heating systems. The kit includes: Testo 115i clamp thermometer, testo 510i differential pressure measuring instrument, and testo 805i infrared thermometer.
Merná jednotka: 1 * 1 KIT
Product Image-5254.9025

BROXO salt, granules 6 - 15 mm

Katalógové číslo: (5254.9025)
Dodávateľ: VWR Chemicals
Opis: Broxo water softener salt allows for problem free water softening that gives a great performance and is efficient in use. It is a very pure high-pressure compacted vacuum salt that dissolves evenly and gradually and is applicable to domestic and industrial installations. Broxo water softener can be used for both domestic and industrial use. The granules dissolves completely and evenly to leave no residual substances. The granules measure from 6mm up to 15mm and provide excellent performance. Also known as rock salt.
Merná jednotka: 1 * 25 kg

KBÚ – slovenskú verziu si vyžiadajte na regulatory.cz@avatorsciences.com


Product Image-GRSG600407

Digital vacuum - / barometer, GMH3161-12

Katalógové číslo: (GRSG600407)
Dodávateľ: GHM MESSTECHNIK
Opis: This handheld meter with integrated absolute pressure sensor is suitable for measurements in air and non corrosive and non ionizing gases and liquids.
Merná jednotka: 1 * 1 items
Image Unavailable-BOSSBS-9491R-A488

Anti-INIP Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalógové číslo: (BOSSBS-9491R-A488)
Dodávateľ: BIOSS INC
Opis: The SOSS (Sensor of single-strand DNA) complex consists of multiple proteins that promote DNA repair and G2/M checkpoint downstream of the MRN (Mre11, Rad50 and Nbs1) complex. The complex is composed of SSBP1, INTS3 and C9orf80. Specifically, the SOSS complex binds to ssDNA at DNA lesions that influences diverse endpoints in the cellular DNA damage response. The complex is required for efficient homologous recombination-dependent repair of double-stranded breaks and ATM-dependent signaling pathways. C9orf80, also known as SOSS complex subunit C and Single-stranded DNA-binding protein-interacting protein 1 (SSBIP1), is a 104 amino acid nuclear protein that is a component of the SOSS complex. Upon DNA damage, C9orf80 along with other components of the SOSS complex migrate to the nucleus. There are two isoforms of C9orf80 that are produced as a result of alternative splicing events.
Merná jednotka: 1 * 100 µl
Product Image-UPCHP-450

Micro-splitter valves, Upchurch Scientific®

Katalógové číslo: (UPCHP-450)
Dodávateľ: UPCHURCH SCIENTIFIC
Opis: Designed to accurately split and control the low flow stream of a single incoming supply.
Merná jednotka: 1 * 1 items
Product Image-620-2632

VWR® Traceable®, USB data logging barometer,

Katalógové číslo: (620-2632)
Dodávateľ: VWR Collection
Opis: The VWR® Traceable® memory loc, USB, data logging barometer simultaneously monitors barometric pressure, temperature and humidity. This device can be used in 21 CFR 11 environments.
Merná jednotka: 1 * 1 items
Product Image-99107.230

VWR®, Distillation standards for the petroleum industry, Certified Reference Materials

Dodávateľ: VWR Chemicals
Opis: Distillation Certified Reference Materials are for the verification of laboratory instruments used in testing petroleum and derivative products for distillation at atmospheric pressure according to ASTM D86, IP 123, ISO 3405 and other such equivalent international methodology.

KBÚ – slovenskú verziu si vyžiadajte na regulatory.cz@avatorsciences.com Certifikáty

Product Image-BRAU8722919

Tubings, Original Perfusor®

Dodávateľ: BRAUN
Opis: Original-Perfusor tubings for use with all syringe pumps inferior to four-bar pressure.

Certifikáty

Product Image-HICHHI-583

Avantor® Hichrom, Inlet Solvent Filters

Dodávateľ: HICHROM
Opis: These solvent inlet filters are used at the low pressure inlet side of the pump to help protect check valves, injector and column from particulate contamination from the eluent.

Image Unavailable-BOSSBS-6634R-A750

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalógové číslo: (BOSSBS-6634R-A750)
Dodávateľ: BIOSS INC
Opis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. <i>in vitro</i>, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Merná jednotka: 1 * 100 µl
Product Image-HEWL5183-4647

Inlet liners

Dodávateľ: AGILENT HEWLETT PACKARD
Opis: These inlet liners prevent adsorption and ensure accurate sample transfer onto the GC column through a robust deactivated surface. These liners are recommended for trace level analysis of active analytes. Liners with inert wool retain non-volatiles, prolonging column life and lowering frequency of MS source maintenance.

Image Unavailable-BOSSBS-6634R-A680

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalógové číslo: (BOSSBS-6634R-A680)
Dodávateľ: BIOSS INC
Opis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. <i>in vitro</i>, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6634R-A488

Anti-XPC Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalógové číslo: (BOSSBS-6634R-A488)
Dodávateľ: BIOSS INC
Opis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Merná jednotka: 1 * 100 µl
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Zásoby tejto položky sú obmedzené, no môžu sa nachádzať v inom sklade blízko pri vás. Uistite sa prosím, že ste prihlásený/á na tejto lokalite, aby sa mohli zobraziť dostupné zásoby. Ak sa stále zobrazuje zavolajte a potrebujete pomoc, zavolajte nám prosím na číslo +43 1 97002 - 0.
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