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Image Unavailable-BOSSBS-6634R-HRP

Anti-XPC Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalógové číslo: (BOSSBS-6634R-HRP)
Dodávateľ: BIOSS INC
Opis: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Merná jednotka: 1 * 100 µl
Product Image-731-0750

Sealing tape, light blocking, non-fluorescent, Nunc™

Katalógové číslo: (731-0750)
Dodávateľ: Thermo Fisher Scientific
Opis: Vinyl film with pressure sensitive acrylate adhesive. For application to plate top or bottom, to protect light sensitive samples.
Merná jednotka: 1 * 50 items

Environmentally Preferable


Nové řešení transparentnosti pro evropské zákazníky

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Zlepšení rozmístění zásob

Product Image-BRDY150759

BradyJet™ J2000 Safety Marine Labels, White

Dodávateľ: BRADY
Opis: The British standard BS 5609 sets durability criteria for printed pressure-sensitive, adhesive-coated labels used when shipping chemical drums by sea.

Product Image-BRAU8255253

Tubings, Original Perfusor®

Dodávateľ: BRAUN
Opis: Original-Perfusor tubings for use with all syringe pumps inferior to four-bar pressure.

Certifikáty

Image Unavailable-2879925-U

Inlet liners, FocusLiner™, Supelco®

Dodávateľ: Merck
Opis: FocusLiner™ inlet liners are designed with wool plug to promote the rapid vaporisation of the entire sample, minimise mass discrimination, and prevent non-volatile material from entering the column. It incorporates a unique design to prevent the shifting of the wool plug during repeated injections or sudden inlet pressure changes. These liners are suitable for Agilent, Perkinelmer, Shimadzu, Finnigan, Varian and Thermo scientific equipped with split/splitless inlets.

Product Image-731-0452

Adhesive qPCR film seals, QuickSeal qPCR Crystal™

Dodávateľ: iST Scientific Ltd
Opis: Clear, non-tacky, pressure sensitive film for qPCR plates (96- or 384-well) and situations where fluorescence is experienced.

Product Image-28466.292

Molekulové síto A4, (0,4 nm, 4 Å), beads, GPR RECTAPUR® 1.6 - 2.5 mm

Dodávateľ: VWR Chemicals
Opis: VWR® 4Å Molecular Sieve is a widely used adsorbent for many different applications. It exhibits high water adsorption capacity at low partial pressures and at temperatures up to 100°C. This molecular sieve is commonly used for drying of organic liquids (solvents, oils, gasolinea and other saturated hydrocarbons, air, liquid gases (propane, butane), as well as noble and other gases (H2, N2, He, Ar, etc.).

KBÚ – slovenskú verziu si vyžiadajte na regulatory.cz@avatorsciences.com Certifikáty

Image Unavailable-181-0362

Scroll pump, XDS series

Katalógové číslo: (181-0362)
Dodávateľ: EDWARDS HIGH VACUUM METTLER
Opis: These XDS series pumps are completely oil free, dry scroll and improved on their pumping speeds, combined with lower ultimate pressures, lower power consumption and lower noise. Gas ballast allows for pumping of condensable vapours including water, solvents, dilute acids and bases. It also feature the latest in tip seal technology giving significantly longer life between tip seal changes. Comes with integrated inverter drive with auto sensing voltage input delivers optimised pumping performance. The pumps are completely field serviceable.
Merná jednotka: 1 * 1 items
Image Unavailable-42757.A7

Silikagel 60 0.060-0.2mm (70-230 mesh), with fluorescent indicator

Dodávateľ: Thermo Fisher Scientific
Opis: Silica gel 60 is used as carriers, processing aids, anti-caking and free-flow agents in animal feed. Defoamer applications such as paint, food, paper, textile and other industrial applications. Synthetic silicon dioxides are used as a rheology control agent in plastics. It is also used in dry column chromatography without applied pressure (gravity pulled).

KBÚ – slovenskú verziu si vyžiadajte na regulatory.cz@avatorsciences.com Certifikáty

Product Image-HECH40850002

Pressure bulbs

Dodávateľ: GLASWARENFABRIK KARL HECHT
Opis: simple: with 2 valves – made of soft PVC (cadmium-free)
double: with valve - made of soft PVC (cadmium-free), ball in the net made of latex

Image Unavailable-MMMA7100260622

Filters, DT

Katalógové číslo: (MMMA7100260622)
Dodávateľ: 3M
Opis: For effective protection against a range of particulates, gases, and vapours, or combination hazards, use 3M™ filters DT series. Suitable for use with certain 3M™ half and full-face tight-fitting respirators in negative-pressure mode as well as 3M™ powered air respirator system PF-600E+ series.
Merná jednotka: 1 * 10 items
Product Image-620-1844

Záznamníky teploty a vlhkosti, testo 175 a 176

Dodávateľ: TESTO
Opis: Záznamníky testo 175 jsou multifunkční kompaktní záznamníky pro měření teploty a vlhkosti. Záznamníky testo 176 jsou robustní a pevné záznamníky vhodné pro náročné aplikace.

Product Image-BRDY148666

Labels for BradyJet J5000 lab printer

Dodávateľ: BRADY
Opis: This indoor marking film is an aqueous, inkjet printable, flexible, matte finish, pressure sensitive adhesive product that is designed to be used with the BradyJet™ J5000 colour label printer.

Image Unavailable-BOSSBS-0356R-CY7

Anti-NOS3 Rabbit Polyclonal Antibody (Cy7®)

Katalógové číslo: (BOSSBS-0356R-CY7)
Dodávateľ: BIOSS INC
Opis: Digoxin is a beta blocker drug originally derived from the foxglove plant, Digitalis lanata. Digoxin is used primarily to improve the pumping ability of the heart in congestive heart failure (CHF), and treat problems such as high blood pressure. It is also used to help normalize some dysrhythmias (abnormal types of heartbeat).
Merná jednotka: 1 * 100 µl
Product Image-201-0290

Pressure-relief valve with manual ventilation, BOLA

Katalógové číslo: (201-0290)
Dodávateľ: Bohlender
Opis: Valve made from PPS with flow body made from PTFE. Can be used as a pressure relief valve with adjustable control of pressure or as a valve to prevent a fall in pressure during the filling process. Flow body with 2 GL 18 threaded connectors and valve with toggle for manual venting by tightening, set screw and lock nut to adjust and fix the application pressure in the range from 0,1 to 10 bar (factory setting 1,5 bar).
Merná jednotka: 1 * 1 items
Product Image-7024-02

Silikagely pro preparativní chromatografii, nízkotlaké, J.T.Baker®

Dodávateľ: Avantor
Opis: Ty se používají v nízkotlaké preparativní chromatografii. Specifikace sít zajišťuje, že v produktu není žádný přebytek jemných částic, které by mohly ovlivnit průtok a výkon separace.

KBÚ – slovenskú verziu si vyžiadajte na regulatory.cz@avatorsciences.com Certifikáty

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Zásoby tejto položky sú obmedzené, no môžu sa nachádzať v inom sklade blízko pri vás. Uistite sa prosím, že ste prihlásený/á na tejto lokalite, aby sa mohli zobraziť dostupné zásoby. Ak sa stále zobrazuje zavolajte a potrebujete pomoc, zavolajte nám prosím na číslo +43 1 97002 - 0.
Daná chemikália je regulovaná podľa platnej legislatívy a bude vyžadované vyplnenie formulára. Jeho včasným vyplnením urýchlite dodanie produktu.
-Na zakúpenie tejto položky môže byť potrebná dodatočná dokumentácia. Ak to bude potrebné, skontaktuje sa s vami zástupca spoločnosti VWR.
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Tento produkt už nie je dostupný. Môžu byť k dispozícii alternatívy, ktoré sa dajú vyhľadať pomocou katalógového čísla VWR uvedeného vyššie. Ak potrebujete ďalšiu pomoc, zavolajte prosím na zákaznícky servis spoločnosti VWR na čísle +43 1 97002 - 0.
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