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Universal pathogen DNA kit, Mag-Bind®

Dodávateľ: OMEGA BIOTEK
Opis: The Mag-Bind® Universal Pathogen DNA 96 Kit allows rapid and reliable isolation of high-quality pathogen and host genomic DNA from tissue samples. Up to a 30 mg tissue sample is recommended and can be processed in less than 60 minutes. The system allows for automation after sample lysis via Hamilton STAR™, Thermo KingFisher™ Flex, Applied Biosystems® MagMAX™, Qiagen Biosprint, and other liquid handling instruments.

KBÚ – slovenskú verziu si vyžiadajte na regulatory.cz@avatorsciences.com Certifikáty

Image Unavailable-BOSSBS-10489R-A750

Anti-HHV DNA polymerase catalytic subunit Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalógové číslo: (BOSSBS-10489R-A750)
Dodávateľ: BIOSS INC
Opis: Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein. Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction. Therefore, it can catalyse the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication.
Merná jednotka: 1 * 100 µl

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Anti-MPG Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalógové číslo: (BOSSBS-2412R-A350)
Dodávateľ: BIOSS INC
Opis: MPG (N-methylpurine DNA glycosylase, or 3-methyladenine (3MeA) DNA glycosylase) repairs the 3MeA lethal lesion blocking DNA replication in Escherichia coli. Analysis of human cDNA libraries found a cDNA that would hybridize to human genomic DNA but not to E. coli or yeast DNA. This MPG gene has been mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2412R-CY3

Anti-MPG Rabbit Polyclonal Antibody (Cy3®)

Katalógové číslo: (BOSSBS-2412R-CY3)
Dodávateľ: BIOSS INC
Opis: MPG (N-methylpurine DNA glycosylase, or 3-methyladenine (3MeA) DNA glycosylase) repairs the 3MeA lethal lesion blocking DNA replication in Escherichia coli. Analysis of human cDNA libraries found a cDNA that would hybridize to human genomic DNA but not to E. coli or yeast DNA. This MPG gene has been mapped to human chromosome 16 by analysis of a panel of DNAs from mouse/human and hamster/human hybrid cell lines.
Merná jednotka: 1 * 100 µl
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MicroElute® Cycle-Pure & Gel Extraction Kit, Omega Bio-tek

Dodávateľ: OMEGA BIOTEK
Opis: MicroElute® Clean Up system, designed for rapid DNA clean up.

KBÚ – slovenskú verziu si vyžiadajte na regulatory.cz@avatorsciences.com

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Food DNA kit, E.Z.N.A.®

Dodávateľ: OMEGA BIOTEK
Opis: The E.Z.N.A.® Food DNA Kit allows rapid and reliable isolation of high quality DNA from complex matrixes such as processed food, chocolate, cereals and meat.

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Product Image-D3485-00

E.Z.N.A.® Plant & Fungal DNA Kit

Dodávateľ: OMEGA BIOTEK
Opis: Isolate DNA from plant or fungal samples using spin columns.

KBÚ – slovenskú verziu si vyžiadajte na regulatory.cz@avatorsciences.com Certifikáty

Image Unavailable-BOSSBS-2980R-A488

Anti-FUS Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalógové číslo: (BOSSBS-2980R-A488)
Dodávateľ: BIOSS INC
Opis: Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1210R-CY7

Anti-BRCA2 Rabbit Polyclonal Antibody (Cy7®)

Katalógové číslo: (BOSSBS-1210R-CY7)
Dodávateľ: BIOSS INC
Opis: Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed duplexes and replication fork structures. May play a role in the extension step after strand invasion at replication-dependent DNA double-strand breaks; together with PALB2 is involved in both POLH localization at collapsed replication forks and DNA polymerization activity. In concert with NPM1, regulates centrosome duplication. Interacts with the TREX-2 complex (transcription and export complex 2) subunits PCID2 and DSS1, and is required to prevent R-loop-associated DNA damage and thus transcription-associated genomic instability. Silencing of BRCA2 promotes R-loop accumulation at actively transcribed genes in replicating and non-replicating cells, suggesting that BRCA2 mediates the control of R-loop associated genomic instability, independently of its known role in homologous recombination (PubMed:24896180).
Merná jednotka: 1 * 100 µl
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DNA isolation kit, EPIXTRACT®

Dodávateľ: ENZO LIFE SCIENCES
Opis: EPIXTRACT® DNA isolation kit provides a simple method to isolate DNA from plasma, serum, and body fluids.

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Product Image-D3396-02

E.Z.N.A.® Tissue DNA Kit

Dodávateľ: OMEGA BIOTEK
Opis: Souprava E.Z.N.A.® tissue DNA kit nabízí jednoduchou, rychlou a cenově výhodnou metodu pro izolaci DNA ze široké škály typů vzorků, včetně čerstvých nebo zmražených živočišných buněk a tkání. Po lyzi buněk může být purifikace DNA hotová do 30 minut. Najednou může být pomocí jednoduchého E.Z.N.A.® tissue DNA protokolu snadno zpracováno až 30 mg tkáně. Souprava využívá centrifugační kolonky a umožňuje zpracovávat jeden vzorek či více vzorků současně. Nejsou nutné extrakce fenolem/chloroformem ani časově náročné kroky jako precipitace izopropanolem nebo ethanolem. DNA purifikovaná za využití soupravy E.Z.N.A.® tissue DNA kit je vhodná pro většinu následných aplikací, jako jsou PCR, southern blot a restrikční enzymatické štěpení.

KBÚ – slovenskú verziu si vyžiadajte na regulatory.cz@avatorsciences.com Certifikáty

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Anti-SIRT6 Rabbit Polyclonal Antibody (Cy5.5®)

Katalógové číslo: (BOSSBS-5634R-CY5.5)
Dodávateľ: BIOSS INC
Opis: NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. Required for genomic stability. Regulates the production of TNF protein. Has a role in the regulation of life span (By similarity). Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. On DNA damage, promotes DNA end resection via deacetylation of RBBP8. Has very weak deacetylase activity and can bind NAD(+) in the absence of acetylated substrate.
Merná jednotka: 1 * 100 µl
Product Image-COPA3002C

NAO™ Baskets for Rapid and Efficient DNA Recovery

Dodávateľ: Copan
Opis: <p>NAO® Basket for rapid and efficient DNA recovery. This is a semi-permeable system designed for releasing and concentrating human DNA from swab samples or other specimens during the extraction step. Lysis in the NAO® Basket: NAO® Basket retains the lysis buffer during the lysis step of the forensic sample.</p>

Image Unavailable-BOSSBS-5634R-A750

Anti-SIRT6 Ser338 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalógové číslo: (BOSSBS-5634R-A750)
Dodávateľ: BIOSS INC
Opis: NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. Required for genomic stability. Regulates the production of TNF protein. Has a role in the regulation of life span (By similarity). Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. On DNA damage, promotes DNA end resection via deacetylation of RBBP8. Has very weak deacetylase activity and can bind NAD(+) in the absence of acetylated substrate.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5634R-A488

Anti-SIRT6 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalógové číslo: (BOSSBS-5634R-A488)
Dodávateľ: BIOSS INC
Opis: NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. Required for genomic stability. Regulates the production of TNF protein. Has a role in the regulation of life span (By similarity). Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. On DNA damage, promotes DNA end resection via deacetylation of RBBP8. Has very weak deacetylase activity and can bind NAD(+) in the absence of acetylated substrate.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5634R-A555

Anti-SIRT6 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalógové číslo: (BOSSBS-5634R-A555)
Dodávateľ: BIOSS INC
Opis: NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. Required for genomic stability. Regulates the production of TNF protein. Has a role in the regulation of life span (By similarity). Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. On DNA damage, promotes DNA end resection via deacetylation of RBBP8. Has very weak deacetylase activity and can bind NAD(+) in the absence of acetylated substrate.
Merná jednotka: 1 * 100 µl
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