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Image Unavailable-BOSSBS-6178R-A750

Anti-RAB20 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalógové číslo: (BOSSBS-6178R-A750)
Dodávateľ: BIOSS INC
Opis: Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-4232R

Anti-ATG16L2 Rabbit Polyclonal Antibody

Katalógové číslo: (BOSSBS-4232R)
Dodávateľ: BIOSS INC
Opis: May play a role in autophagy.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13016R-A750

Anti-DNA polymerase eta Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalógové číslo: (BOSSBS-13016R-A750)
Dodávateľ: BIOSS INC
Opis: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1389R-CY5.5

Anti-Cyclin G Rabbit Polyclonal Antibody (Cy5.5®)

Katalógové číslo: (BOSSBS-1389R-CY5.5)
Dodávateľ: BIOSS INC
Opis: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-10278R

Anti-PIK3CG Rabbit Polyclonal Antibody

Katalógové číslo: (BOSSBS-10278R)
Dodávateľ: BIOSS INC
Opis: This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008].
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11570R-CY7

Anti-WWC1 Rabbit Polyclonal Antibody (Cy7®)

Katalógové číslo: (BOSSBS-11570R-CY7)
Dodávateľ: BIOSS INC
Opis: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11570R-CY5

Anti-WWC1 Rabbit Polyclonal Antibody (Cy5®)

Katalógové číslo: (BOSSBS-11570R-CY5)
Dodávateľ: BIOSS INC
Opis: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7882R-HRP

Anti-UBE2V1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalógové číslo: (BOSSBS-7882R-HRP)
Dodávateľ: BIOSS INC
Opis: Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13489R-A555

Anti-GOLPH3L Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalógové číslo: (BOSSBS-13489R-A555)
Dodávateľ: BIOSS INC
Opis: The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in Golgi trafficking.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13489R-CY5

Anti-GOLPH3L Rabbit Polyclonal Antibody (Cy5®)

Katalógové číslo: (BOSSBS-13489R-CY5)
Dodávateľ: BIOSS INC
Opis: The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in Golgi trafficking.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2748R-A647

Anti-BLNK Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalógové číslo: (BOSSBS-2748R-A647)
Dodávateľ: BIOSS INC
Opis: Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2748R-FITC

Anti-BLNK Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalógové číslo: (BOSSBS-2748R-FITC)
Dodávateľ: BIOSS INC
Opis: Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3054R-A350

Anti-BLNK Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalógové číslo: (BOSSBS-3054R-A350)
Dodávateľ: BIOSS INC
Opis: Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5123R-CY5

Anti-AGR2 Rabbit Polyclonal Antibody (Cy5®)

Katalógové číslo: (BOSSBS-5123R-CY5)
Dodávateľ: BIOSS INC
Opis: Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6461R-A680

Anti-NF-ATc4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalógové číslo: (BOSSBS-6461R-A680)
Dodávateľ: BIOSS INC
Opis: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. Transcriptionally repressed by estrogen receptors; this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation. May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-7836R-CY5.5

Anti-DCTN2 Rabbit Polyclonal Antibody (Cy5.5®)

Katalógové číslo: (BOSSBS-7836R-CY5.5)
Dodávateľ: BIOSS INC
Opis: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
Merná jednotka: 1 * 100 µl
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