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Katalógové číslo: (BOSSBS-3851R-CY7)
Dodávateľ: BIOSS INC
Opis: Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-11995R)
Dodávateľ: BIOSS INC
Opis: Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading. Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT. Plays a role in the regulation of mast cell degranulation. Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF signaling. Plays a role in cell scattering and cell migration in response to HGF-induced activation of EZR. Phosphorylates BCR and down-regulates BCR kinase activity. Phosphorylates HCLS1/HS1, PECAM1, STAT3 and TRIM28.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-2740R-CY3)
Dodávateľ: BIOSS INC
Opis: p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-4910R-HRP)
Dodávateľ: BIOSS INC
Opis: Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-7754R-A555)
Dodávateľ: BIOSS INC
Opis: Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-1363R-A647)
Dodávateľ: BIOSS INC
Opis: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-2693R-CY5.5)
Dodávateľ: BIOSS INC
Opis: Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-4248R-FITC)
Dodávateľ: BIOSS INC
Opis: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-2740R-A555)
Dodávateľ: BIOSS INC
Opis: p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-1990R-CY5)
Dodávateľ: BIOSS INC
Opis: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-1588R-A647)
Dodávateľ: BIOSS INC
Opis: Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-1588R-A555)
Dodávateľ: BIOSS INC
Opis: Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-3020R-CY3)
Dodávateľ: BIOSS INC
Opis: Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-12086R-FITC)
Dodávateľ: BIOSS INC
Opis: Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-12086R-CY3)
Dodávateľ: BIOSS INC
Opis: Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-6467R-A680)
Dodávateľ: BIOSS INC
Opis: Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions.
Merná jednotka: 1 * 100 µl


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