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Katalógové číslo: (BOSSBS-7887R)

Dodávateľ: BIOSS INC

Opis: Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A).

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-2740R-CY5)

Dodávateľ: BIOSS INC

Opis: p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-2487R-CY5.5)

Dodávateľ: BIOSS INC

Opis: May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of apoptosis.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-2740R-A488)

Dodávateľ: BIOSS INC

Opis: p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-2740R-HRP)

Dodávateľ: BIOSS INC

Opis: p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-5844R)

Dodávateľ: BIOSS INC

Opis: May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-7112R-A555)

Dodávateľ: BIOSS INC

Opis: G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. Plays an important role in the regulation of sprouting angiogenesis and vascular maturation. Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development. Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs. Plays a role in the migration of osteoclast precursor cells, the regulation of bone mineralization and bone homeostasis (By similarity). Plays a role in responses to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-3573R-A680)

Dodávateľ: BIOSS INC

Opis: Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-0018R-CY7)

Dodávateľ: BIOSS INC

Opis: Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-5123R-FITC)

Dodávateľ: BIOSS INC

Opis: Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-5123R-A488)

Dodávateľ: BIOSS INC

Opis: Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-5123R-A350)

Dodávateľ: BIOSS INC

Opis: Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-3068R-HRP)

Dodávateľ: BIOSS INC

Opis: Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-3851R-A488)

Dodávateľ: BIOSS INC

Opis: Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-7836R-A555)

Dodávateľ: BIOSS INC

Opis: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-2687R-HRP)

Dodávateľ: BIOSS INC

Opis: Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in the DNA damage checkpoint response.

Merná jednotka: 1 * 100 µl

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