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Katalógové číslo: (BOSSBS-12630R-A647)
Dodávateľ: BIOSS INC
Opis: This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010]
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-12630R-CY3)
Dodávateľ: BIOSS INC
Opis: This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010]
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-12630R-HRP)
Dodávateľ: BIOSS INC
Opis: This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010]
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-10522R-CY3)
Dodávateľ: BIOSS INC
Opis: This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010]
Merná jednotka: 1 * 100 µl


Katalógové číslo: (BOSSBS-12630R-FITC)
Dodávateľ: BIOSS INC
Opis: This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010]
Merná jednotka: 1 * 100 µl


Katalógové číslo: (PRSI92-285)
Dodávateľ: PROSCI
Opis: Lymphocyte cytosolic protein 2(LCP2)contains a SAM domain and a SH2 domain. It is highly expressed in spleen, thymus and peripheral blood leukocytes, T-cell and monocytic cell lines, but expressed at lower level in B-cell lines. LCP2 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. It is phosphorylated after T-cell receptor activation by ZAP70, ITK and TXK, which leads to the up-regulation of Th1 preferred cytokine IL-2 during post-translational modification. Studies using LCP2-deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.
Merná jednotka: 1 * 50 µG


Katalógové číslo: (SIALSAB4503108-100)
Dodávateľ: Merck
Opis: ANTI-ZAP-70 1 * 100 µG
Merná jednotka: 1 * 100 µG


Katalógové číslo: (SIALSAB4503107-100)
Dodávateľ: Merck
Opis: ANTI-ZAP-70 1 * 100 µG
Merná jednotka: 1 * 100 µG


Katalógové číslo: (SIALSAB4503106-100)
Dodávateľ: Merck
Opis: ANTI-ZAP-70 1 * 100 µG
Merná jednotka: 1 * 100 µG


Katalógové číslo: (SIALSAB4504571-100)
Dodávateľ: Merck
Opis: ANTI-PHOSPHO-ZAP-70 (PTYR493) 1 * 100 µG
Merná jednotka: 1 * 100 µG


Katalógové číslo: (SIALSAB4504012-100)
Dodávateľ: Merck
Opis: ANTI-PHOSPHO-ZAP-70 (PTYR315) 1 * 100 µG
Merná jednotka: 1 * 100 µG


Katalógové číslo: (SIALZ2126-20UG)
Dodávateľ: Merck
Opis: ZAP-70 TYROSINE KINASE, HISTIDINE-*TAGGE 1 * 1 MJ
Merná jednotka: 1 * 1 Each


Katalógové číslo: (SIALSAB4504011-100)
Dodávateľ: Merck
Opis: ANTI-PHOSPHO-ZAP-70 (PTYR292) 1 * 100 µG
Merná jednotka: 1 * 100 µG


Katalógové číslo: (SIALZ0627-200UL)
Dodávateľ: Merck
Opis: MONOCLONAL ANTI-ZAP-70, CLONE 1E7.2 1 * 200 µl
Merná jednotka: 1 * 200 µl


Katalógové číslo: (SIALSAB4701001-100)
Dodávateľ: Merck
Opis: ANTI-ZAP-70 ANTIBODY PRODUCED IN RABBIT 1 * 100 µG
Merná jednotka: 1 * 100 µG


Katalógové číslo: (CAYM32334-100)
Dodávateľ: CAYMAN
Opis: ZAP-70 N-TERM RABBIT MONOCLONAL ANTIBODY 1 * 100 µl
Merná jednotka: 1 * 100 µl


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