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Image Unavailable-BOSSBS-8339R-CY5.5

Anti-PANK3 Rabbit Polyclonal Antibody (Cy5.5®)

Katalógové číslo: (BOSSBS-8339R-CY5.5)
Dodávateľ: BIOSS INC
Opis: The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA) biosynthesis. Coenzyme A is an important coenzyme involved in the synthesis and oxidation of fatty acids, as well as the oxidation of pyruvate in the citric acid (Krebs) cycle. Pantothenate kinase 3 (PANK3) is a 370 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration. Localized to the cytoplasm, PANK3 is regulated by feedback inhibition by CoA and its thioesters. PANK3 transfers a phosphate from ATP to pantothenate (Vitamin B5), resulting in formation of 4’-phosphopantothenate. Closely related to its family members, PANK1, PANK2 and PANK4, PANK3 is highly expressed in liver. Pantothenate kinase associated neurodegeneration (PKAN) results from mutations in the gene encoding PANK2, the only mitochondria targeted human PANK.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-8329R-FITC

Anti-SRXN1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalógové číslo: (BOSSBS-8329R-FITC)
Dodávateľ: BIOSS INC
Opis: Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-12461R-CY5

Anti-ALDH9A1 Rabbit Polyclonal Antibody (Cy5®)

Katalógové číslo: (BOSSBS-12461R-CY5)
Dodávateľ: BIOSS INC
Opis: Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH9A1 (aldehyde dehydrogenase family 9 member A1), also known as E3, ALDH4, ALDH7, ALDH9 or TMABADH, is a 494 amino acid cytoplasmic protein that is highly expressed in adult liver, skeletal muscle, kidney and embryonic brain. ALDH9A1 converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine and catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in a NAD-dependent reaction.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6716R-HRP

Anti-UOXP Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalógové číslo: (BOSSBS-6716R-HRP)
Dodávateľ: BIOSS INC
Opis: Uricase catalyzes the oxidation of uric acid to 5 hydroxyisourate which spontaneously decomposes to form allantoin.
Merná jednotka: 1 * 100 µl
Image Unavailable-CAYM53400-100

(12Z)-9,10-Dihydroxy-12-octadecenoic acid ≥98.0%

Dodávateľ: CAYMAN
Opis: Leukotoxin is the 9(10) epoxide of linoleic acid, generated by neutrophils during the oxidative burst. This unstable compound is rapidly degraded by epoxide hydrolases to form the diol, (±)9(10)-DiHOME. Mitochondrial dysfunction, vasodilation and apoptosis are features of leukotoxin toxicity. In renal phydrolysesroximal tubular cells, the diol hydrolysis products of leukotoxin, such as (±)9(10)-DiHOME, have been directly implicated as the cytotoxic agent responsible for cell death.

Image Unavailable-BOSSBS-12461R-A555

Anti-ALDH9A1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalógové číslo: (BOSSBS-12461R-A555)
Dodávateľ: BIOSS INC
Opis: Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH9A1 (aldehyde dehydrogenase family 9 member A1), also known as E3, ALDH4, ALDH7, ALDH9 or TMABADH, is a 494 amino acid cytoplasmic protein that is highly expressed in adult liver, skeletal muscle, kidney and embryonic brain. ALDH9A1 converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine and catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in a NAD-dependent reaction.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-8552R-HRP

Anti-XDH Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalógové číslo: (BOSSBS-8552R-HRP)
Dodávateľ: BIOSS INC
Opis: Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).Involvement in disease;Defects in XDH are the cause of xanthinuria type 1 (XU1) . Xanthinuria is characterized by excretion of very large amounts of xanthine in the urine and a tendency to form xanthine stones. Uric acid is strikingly diminished in serum and urine. XU1 is due to isolated xanthine dehydrogenase. XU1 patients can metabolize allopurinol.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5048R-A750

Anti-CROT Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalógové číslo: (BOSSBS-5048R-A750)
Dodávateľ: BIOSS INC
Opis: Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl-CoA, to its corresponding carnitine ester.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5048R-HRP

Anti-CROT Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalógové číslo: (BOSSBS-5048R-HRP)
Dodávateľ: BIOSS INC
Opis: Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl-CoA, to its corresponding carnitine ester.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-3661R-HRP

Anti-HADH Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalógové číslo: (BOSSBS-3661R-HRP)
Dodávateľ: BIOSS INC
Opis: HADHSC functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-10162R-CY5

Anti-ALDH1A1 Rabbit Polyclonal Antibody (Cy5®)

Katalógové číslo: (BOSSBS-10162R-CY5)
Dodávateľ: BIOSS INC
Opis: Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity).
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11997R-CY7

Anti-DDAH1 Rabbit Polyclonal Antibody (Cy7®)

Katalógové číslo: (BOSSBS-11997R-CY7)
Dodávateľ: BIOSS INC
Opis: DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production (1,2). Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation (3). DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) (4). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues (1).
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11997R-A680

Anti-DDAH1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalógové číslo: (BOSSBS-11997R-A680)
Dodávateľ: BIOSS INC
Opis: DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyses dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) (4). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.
Merná jednotka: 1 * 100 µl
Image Unavailable-CAYM17942-1

Standards for saturated/monounsaturated fatty acids, LC-MS mixture

Katalógové číslo: (CAYM17942-1)
Dodávateľ: CAYMAN
Opis: Saturated or monounsaturated fatty acid LC-MS mixture contains various saturated or unsaturated fatty acids. The mixture is supplied in an amber ampule in which the headspace has been purged with argon to prevent lipid oxidation. This product has been designed for direct use in LC-MS applications.
Merná jednotka: 1 * 1 items

KBÚ – slovenskú verziu si vyžiadajte na regulatory.cz@avatorsciences.com


Image Unavailable-BOSSBS-5018R-FITC

Anti-ACADVL Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalógové číslo: (BOSSBS-5018R-FITC)
Dodávateľ: BIOSS INC
Opis: ACADVL (acyl-Coenzyme A dehydrogenase, very long chain) catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. It is specific to esters of long-chain and very long chain fatty acids such as palmitoyl-CoA and stearoyl-CoA. Deficiencies in ACADVL are associated with reduced myocardial fatty acid beta-oxidation and cardiomyopathy.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5018R-A750

Anti-ACADVL Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Katalógové číslo: (BOSSBS-5018R-A750)
Dodávateľ: BIOSS INC
Opis: ACADVL (acyl-Coenzyme A dehydrogenase, very long chain) catalyses the first step of the mitochondrial fatty acid beta-oxidation pathway. It is specific to esters of long-chain and very long chain fatty acids such as palmitoyl-CoA and stearoyl-CoA. Deficiencies in ACADVL are associated with reduced myocardial fatty acid beta-oxidation and cardiomyopathy.
Merná jednotka: 1 * 100 µl
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