Hľadali ste: O-Methyl-L-tyrosine

Katalógové číslo: (BOSSBS-5624R-A555)

Dodávateľ: BIOSS INC

Opis: Src (also known as pp60src) is a non receptor Tyrosine Kinase involved in signal transduction in many biological systems and implicated in the development of human tumors. There are two critical phosphorylation sites of tyrosine on Src, tyrosine 418 and tyrosine 529 (referring to human Src sequence). The tyrosine 418 is located in the catalytic domain and is one of the autophosphorylation sites. Full catalytic activity of Src requires phosphorylation of tyrosine 418. The tyrosine 529 is located near the carboxyl terminus of Src and acts as a negative regulator, in that Src is held in the inactive form through an intramolecular interaction between the SH2 domain and the carboxyl terminus when tyrosine 529 is phosphorylated by Csk. This conformation blocks phosphorylation of tyrosine 418 at the catalytic domain, thereby preventing Src activation. When tyrosine 529 is dephosphorylated, tyrosine 418 can be maximally phosphorylated and Src becomes active. Src is a proto oncogene that may play a role in the regulation of embryonic development and cell growth. Mutations in this gene could be involved in the malignant progression of colon cancer. Immunogen: Synthetic peptide (Human) derived from the region of Src that contains tyrosine 529, based on the human sequence. The sequence is conserved in mouse (tyrosine 534), chicken (tyrosine 527) and frog (tyrosine 525).

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-5624R-A488)

Dodávateľ: BIOSS INC

Opis: Src (also known as pp60src) is a non receptor Tyrosine Kinase involved in signal transduction in many biological systems and implicated in the development of human tumors. There are two critical phosphorylation sites of tyrosine on Src, tyrosine 418 and tyrosine 529 (referring to human Src sequence). The tyrosine 418 is located in the catalytic domain and is one of the autophosphorylation sites. Full catalytic activity of Src requires phosphorylation of tyrosine 418. The tyrosine 529 is located near the carboxyl terminus of Src and acts as a negative regulator, in that Src is held in the inactive form through an intramolecular interaction between the SH2 domain and the carboxyl terminus when tyrosine 529 is phosphorylated by Csk. This conformation blocks phosphorylation of tyrosine 418 at the catalytic domain, thereby preventing Src activation. When tyrosine 529 is dephosphorylated, tyrosine 418 can be maximally phosphorylated and Src becomes active. Src is a proto oncogene that may play a role in the regulation of embryonic development and cell growth. Mutations in this gene could be involved in the malignant progression of colon cancer. Immunogen: Synthetic peptide (Human) derived from the region of Src that contains tyrosine 529, based on the human sequence. The sequence is conserved in mouse (tyrosine 534), chicken (tyrosine 527) and frog (tyrosine 525).

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (USBIP9109-21)

Dodávateľ: UNITED BIOCHEMICALS

Opis: Anti-Protein Tyrosine Phosphatase Mouse Monoclonal Antibody [clone: 4i12]

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (USBIP9109-40N)

Dodávateľ: UNITED BIOCHEMICALS

Opis: Anti-Protein Tyrosine Phosphatase, Receptor Type N Chicken Polyclonal Antibody

Merná jednotka: 1 * 50 µG

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Katalógové číslo: (USBIP9109-40L2)

Dodávateľ: UNITED BIOCHEMICALS

Opis: Anti-Protein Tyrosine Phosphatase Receptor Type M Rabbit Polyclonal Antibody

Merná jednotka: 1 * 50 µG

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Katalógové číslo: (USBI152063)

Dodávateľ: UNITED BIOCHEMICALS

Opis: Anti-Protein Tyrosine Phosphatase Receptor Type C Mouse Monoclonal Antibody

Merná jednotka: 1 * 200 µG

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Katalógové číslo: (ABCAAB7048-50)

Dodávateľ: ABCAM

Opis: Anti-Nitro tyrosine Mouse Monoclonal Antibody [clone: HM.11]

Merná jednotka: 1 * 50 µG

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Katalógové číslo: (ABCAAB27648-250)

Dodávateľ: ABCAM

Opis: Anti-Nitro tyrosine Goat Polyclonal Antibody (HRP (Horseradish Peroxidase))

Merná jednotka: 1 * 250 µl

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Katalógové číslo: (USBIP9109-40B-PE)

Dodávateľ: UNITED BIOCHEMICALS

Opis: Anti-Protein Tyrosine Phosphatase, Receptor Type sigma Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: 11C621]

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (USBIP9109-40P)

Dodávateľ: UNITED BIOCHEMICALS

Opis: Anti-Protein Tyrosine Phosphatase, Receptor Type N2 Chicken Polyclonal Antibody

Merná jednotka: 1 * 50 µG

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Katalógové číslo: (ABCAAB7225-25)

Dodávateľ: ABCAM

Opis: Anti-Nitro tyrosine Mouse Monoclonal Antibody (Biotin) [clone: HM.11]

Merná jednotka: 1 * 25 µG

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Katalógové číslo: (BOSSBS-10076R-HRP)

Dodávateľ: BIOSS INC

Opis: Tyrosine-protein kinase receptor whose role is not yet clear. ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (USBIP9109-40E)

Dodávateľ: UNITED BIOCHEMICALS

Opis: Anti-Protein Tyrosine Phosphatase, Receptor Type E, Isoform 1 Chicken Polyclonal Antibody

Merná jednotka: 1 * 50 µG

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Katalógové číslo: (ENZOBMLEI3530001)

Dodávateľ: ENZO LIFE SCIENCES

Opis: VEGF receptor tyrosine kinase inhibitor. Inhibits KDR (IC50=100nM) and Flt (IC50=2µM) tyrosine kinases.

Merná jednotka: 1 * 1 mg

New Product Predaj

Katalógové číslo: (BOSSBS-0016R-A680)

Dodávateľ: BIOSS INC

Opis: Neuronal Marker Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's disease.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (USBIP9109-40R2-PE)

Dodávateľ: UNITED BIOCHEMICALS

Opis: Anti-Protein Tyrosine Phosphatase, Receptor Type R Rabbit Polyclonal Antibody (PE (Phycoerythrin))

Merná jednotka: 1 * 200 µl

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