Hľadali ste: Methyl+arachidonate

Katalógové číslo: (BOSSBS-12999R-A750)

Dodávateľ: BIOSS INC

Opis: Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition.

Merná jednotka: 1 * 100 µl

Predaj

Katalógové číslo: (BOSSBS-0420R-A350)

Dodávateľ: BIOSS INC

Opis: Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.

Merná jednotka: 1 * 100 µl

Predaj

Katalógové číslo: (BOSSBS-3251R-FITC)

Dodávateľ: BIOSS INC

Opis: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

Merná jednotka: 1 * 100 µl

Predaj

Katalógové číslo: (BOSSBS-3251R-A680)

Dodávateľ: BIOSS INC

Opis: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyses the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

Merná jednotka: 1 * 100 µl

Predaj

Katalógové číslo: (ENZOALX210879R100)

Dodávateľ: ENZO LIFE SCIENCES

Opis: MDA (Malondialdehyde) is a highly reactive three carbon dialdehyde produced as a byproduct of polyunsaturated fatty acid peroxidation and arachidonic acid metabolism. MDA readily combines with several functional groups on molecules including proteins, lipoproteins, and DNA. MDA modified proteins may show altered physico-chemical behavior and antigenicity. Antibodies to MDA will help to visualize the MDA-adducts.

Merná jednotka: 1 * 100 µl

New Product Predaj

Katalógové číslo: (BOSSBS-12999R)

Dodávateľ: BIOSS INC

Opis: Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition.

Merná jednotka: 1 * 100 µl

Predaj

Katalógové číslo: (BOSSBS-5060R-FITC)

Dodávateľ: BIOSS INC

Opis: FADS1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids from precursor essential polyunsaturated fatty acids, linoleic acid and alphanlinolenic acid. It catalyzes the desaturation of dihomo gamma linoleic acid and eicosatetraenoic acid to generate arachidonic acid and eicosapentaenoic acid respectively.

Merná jednotka: 1 * 100 µl

Predaj

Katalógové číslo: (BOSSBS-5060R-CY7)

Dodávateľ: BIOSS INC

Opis: FADS1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids from precursor essential polyunsaturated fatty acids, linoleic acid and alphanlinolenic acid. It catalyzes the desaturation of dihomo gamma linoleic acid and eicosatetraenoic acid to generate arachidonic acid and eicosapentaenoic acid respectively.

Merná jednotka: 1 * 100 µl

Predaj

Katalógové číslo: (BOSSBS-5060R-HRP)

Dodávateľ: BIOSS INC

Opis: FADS1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids from precursor essential polyunsaturated fatty acids, linoleic acid and alphanlinolenic acid. It catalyzes the desaturation of dihomo gamma linoleic acid and eicosatetraenoic acid to generate arachidonic acid and eicosapentaenoic acid respectively.

Merná jednotka: 1 * 100 µl

Predaj

Katalógové číslo: (BOSSBS-6505R-A555)

Dodávateľ: BIOSS INC

Opis: Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.

Merná jednotka: 1 * 100 µl

Predaj

Katalógové číslo: (BOSSBS-6505R-HRP)

Dodávateľ: BIOSS INC

Opis: Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.

Merná jednotka: 1 * 100 µl

Predaj

Dodávateľ: ENZO LIFE SCIENCES

Opis: Selective, potent cAMP-specific phosphodiesterase inhibitor (PDE IV, IC50=2µM). Inhibits superoxide generation and platelet aggregation stimulated by arachidonic acid. Also inhibits fMLP-induced neutrophil adhesion to vascular endothelial cells.

New Product

Katalógové číslo: (BOSSBS-7556R)

Dodávateľ: BIOSS INC

Opis: Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.

Merná jednotka: 1 * 100 µl

Predaj

Katalógové číslo: (BOSSBS-5060R-A750)

Dodávateľ: BIOSS INC

Opis: FADS1 is a component of a lipid metabolic pathway that catalyses biosynthesis of highly unsaturated fatty acids from precursor essential polyunsaturated fatty acids, linoleic acid and alphanlinolenic acid. It catalyses the desaturation of dihomo gamma linoleic acid and eicosatetraenoic acid to generate arachidonic acid and eicosapentaenoic acid respectively.

Merná jednotka: 1 * 100 µl

Predaj

Katalógové číslo: (USBIA1359-76K)

Dodávateľ: UNITED BIOCHEMICALS

Opis: Anti-ALOX5AP Goat Polyclonal Antibody

Merná jednotka: 1 * 50 µG

Predaj

Katalógové číslo: (BOSSBS-0420R-CY7)

Dodávateľ: BIOSS INC

Opis: Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.

Merná jednotka: 1 * 100 µl

Predaj