Hľadali ste: Forskolin

Dodávateľ: Apollo Scientific

Opis: An activator of adenylate cyclase.

Dodávateľ: ENZO LIFE SCIENCES

Opis: Adenylate cyclase activator

New Product

Katalógové číslo: (1283244.)

Dodávateľ: USP

Opis: USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.

Merná jednotka: 1 * 40 mg

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Dodávateľ: Thermo Fisher Scientific

Opis: Forskolin ≥98%

KBÚ – slovenskú verziu si vyžiadajte na regulatory.cz@avatorsciences.com Certifikáty

Dodávateľ: CAYMAN

Opis: Forskolin

KBÚ – slovenskú verziu si vyžiadajte na regulatory.cz@avatorsciences.com

Dodávateľ: MP BIOMEDICALS

Opis: Forskolin is the major diterpene isolated from the Indian plant Coleus forskohlii. At low doses, Forskolin is a positive inotropic agent in dogs, cats, spontaneously hypertensive and normal rats and in an isolated guinea pig heart (Langendorf) preparation. At higher doses, Forskolin is a hypotensive and vasodilatory agent because of its function as a smooth muscle relaxant. No major side effects are observed at effective doses.

Dodávateľ: Merck

Opis: Forskolin (from Coleus forskohlii), Sigma-Aldrich®

Dodávateľ: Merck

Opis: Forskolin (from Coleus forskohlii), Sigma-Aldrich®

Katalógové číslo: (93049-10MG)

Dodávateľ: Merck

Opis: Organic Standard, Forskolin

Merná jednotka: 1 * 10 mg

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Katalógové číslo: (PRSI26-233)

Dodávateľ: PROSCI

Opis: SAC belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction.The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Merná jednotka: 1 * 50 µG

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Katalógové číslo: (PRSI91-320)

Dodávateľ: PROSCI

Opis: IGFBP-4, whose full name is insulin-like growth factor-binding protein 4, is induced by forskolin and N6, O2’dibutyryl sdenosine 3’, or 5’-cyclic monophosphate. It contains IGFBP N-terminal domain and thyroglobulin type-1 domain, and can bind IGF2. The IGF-binding proteins can prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.

Merná jednotka: 1 * 50 µG

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Katalógové číslo: (PRSI32-191)

Dodávateľ: PROSCI

Opis: Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.This monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lysate.

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (PRSI5453)

Dodávateľ: PROSCI

Opis: FRMPD1 Antibody: The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. FRMPD1 was initially identified through a yeast two-hybrid screening with Activator of G-protein signaling 3 (AGS3), a protein that acts to stabilize the GDP-bound conformation of Gai, as the bait. FRMPD1 binds to the tetratricopeptide repeat of AGS3 and stabilizes AGS3 in a membrane environment. Suppression of FRMPD1 in Cath.a-differentiated neuronal cells decreased the level of endogenous AGS3 in membrane fractions by ~50% and enhanced the inhibition of forskolin-induced increases in cAMP. Co-immunoprecipitation studies indicate that the interaction of AGS3 with FRMPD1 is mutually exclusive with the interaction of AGS3 with Gai3, suggesting that FRMPD1 may position AGS3 in the membrane where it can then interact with Galphai.

Merná jednotka: 1 * 100 µG

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Katalógové číslo: (ABCAAB120058-10)

Dodávateľ: ABCAM

Opis: FORSKOLIN 1 * 10 mg

Merná jednotka: 1 * 10 mg

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Katalógové číslo: (CAYM11664-1)

Dodávateľ: CAYMAN

Opis: 1,9-DIDEOXY FORSKOLIN 1 * 1 mg

Merná jednotka: 1 * 1 mg

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Katalógové číslo: (CAYM11664-500)

Dodávateľ: CAYMAN

Opis: 1,9-DIDEOXY FORSKOLIN 1 * 500 µG

Merná jednotka: 1 * 500 µG

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