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Hľadali ste: D-(-)-Glutamic+acid


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Image Unavailable-APOSOR964505-25G

Boc-D-Glu(Obzl)-OH

Dodávateľ: Apollo Scientific
Opis: Boc-D-Glu(Obzl)-OH

Image Unavailable-H63318.06

H-d-glu-otbu 98%

Dodávateľ: Thermo Fisher Scientific
Opis: H-d-glu-otbu 98%

Certifikáty

Image Unavailable-H63463.14

H-D-Glu(OtBu)-OH 95%

Dodávateľ: Thermo Fisher Scientific
Opis: H-D-Glu(OtBu)-OH 95%

Certifikáty

Image Unavailable-BOSSBS-0400R-CY5.5

Anti-GAD2 Rabbit Polyclonal Antibody (Cy5.5®)

Katalógové číslo: (BOSSBS-0400R-CY5.5)
Dodávateľ: BIOSS INC
Opis: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-0400R-A647

Anti-GAD2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalógové číslo: (BOSSBS-0400R-A647)
Dodávateľ: BIOSS INC
Opis: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
Merná jednotka: 1 * 100 µl
Image Unavailable-APOSOR1150T-10MG

AMPA

Katalógové číslo: (APOSOR1150T-10MG)
Dodávateľ: Apollo Scientific
Opis: A selective agonist of the exitatory neurotransmitter L-glutamic acid. AMPA does not interfere with binding sites for kainic acid in vitro.
Merná jednotka: 1 * 10 mg
Image Unavailable-BOSSBS-13494R-A350

Anti-GOT1L1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalógové číslo: (BOSSBS-13494R-A350)
Dodávateľ: BIOSS INC
Opis: GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13494R-A680

Anti-GOT1L1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalógové číslo: (BOSSBS-13494R-A680)
Dodávateľ: BIOSS INC
Opis: GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.
Merná jednotka: 1 * 100 µl
Image Unavailable-ROCKMB-114-0001

Protease

Katalógové číslo: (ROCKMB-114-0001)
Dodávateľ: ROCKLAND
Opis: Protease <i>S.aureus</i> V8 (endoproteinase-glu-C) specifically cleaves peptide bonds on the COOH-terminal side of either aspartic or glutamic acids. In the presence of ammonium, the enzyme specificity is limited to glutamic sites. It has a molecular weight of 27000 daltons and optimum pH's of 4,0 and 7,8 with hemoglobin as the substrate. Enzyme activity is determined by the casein digestion assay.
Merná jednotka: 1 * 1 mg
Image Unavailable-BOSSBS-13264R-A555

Anti-GADL1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalógové číslo: (BOSSBS-13264R-A555)
Dodávateľ: BIOSS INC
Opis: There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13046R

Anti-EAAT4 Rabbit Polyclonal Antibody

Katalógové číslo: (BOSSBS-13046R)
Dodávateľ: BIOSS INC
Opis: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13264R-HRP

Anti-GADL1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalógové číslo: (BOSSBS-13264R-HRP)
Dodávateľ: BIOSS INC
Opis: There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13046R-CY7

Anti-SLC1A6 Rabbit Polyclonal Antibody (Cy7®)

Katalógové číslo: (BOSSBS-13046R-CY7)
Dodávateľ: BIOSS INC
Opis: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13046R-FITC

Anti-SLC1A6 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalógové číslo: (BOSSBS-13046R-FITC)
Dodávateľ: BIOSS INC
Opis: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
Merná jednotka: 1 * 100 µl
Image Unavailable-H62320.06

Boc-D-Glu-OtBu 95%

Dodávateľ: Thermo Fisher Scientific
Opis: Boc-D-Glu-OtBu 95%

Certifikáty

Image Unavailable-BOSSBS-13263R-CY5

Anti-GAD1/GAD2 Rabbit Polyclonal Antibody (Cy5®)

Katalógové číslo: (BOSSBS-13263R-CY5)
Dodávateľ: BIOSS INC
Opis: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome.
Merná jednotka: 1 * 100 µl
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