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Image Unavailable-BOSSBS-20130R-A750

Anti-FAIM3 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Katalógové číslo: (BOSSBS-20130R-A750)
Dodávateľ: BIOSS INC
Opis: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5930R-CY5

Anti-CENTG1 Rabbit Polyclonal Antibody (Cy5®)

Katalógové číslo: (BOSSBS-5930R-CY5)
Dodávateľ: BIOSS INC
Opis: GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1351R-A680

Anti-Granzyme B and Granzyme H Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalógové číslo: (BOSSBS-1351R-A680)
Dodávateľ: BIOSS INC
Opis: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1351R-A647

Anti-GZMB Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalógové číslo: (BOSSBS-1351R-A647)
Dodávateľ: BIOSS INC
Opis: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1351R-FITC

Anti-GZMB Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Katalógové číslo: (BOSSBS-1351R-FITC)
Dodávateľ: BIOSS INC
Opis: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-4563R-CY5.5

Anti-BCL2 Rabbit Polyclonal Antibody (Cy5.5®)

Katalógové číslo: (BOSSBS-4563R-CY5.5)
Dodávateľ: BIOSS INC
Opis: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-4563R-CY5

Anti-BCL2 Rabbit Polyclonal Antibody (Cy5®)

Katalógové číslo: (BOSSBS-4563R-CY5)
Dodávateľ: BIOSS INC
Opis: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-15533R-HRP

Anti-Bcl-2 Rabbit Polyclonal Antibody (HRP)

Katalógové číslo: (BOSSBS-15533R-HRP)
Dodávateľ: BIOSS INC
Opis: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Merná jednotka: 1 * 100 µl
Product Image-BOSSBS-15533R

Anti-Bcl-2 Rabbit Polyclonal Antibody

Katalógové číslo: (BOSSBS-15533R)
Dodávateľ: BIOSS INC
Opis: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-4563R-CY3

Anti-BCL2 Rabbit Polyclonal Antibody (Cy3®)

Katalógové číslo: (BOSSBS-4563R-CY3)
Dodávateľ: BIOSS INC
Opis: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-19301R-A750

Anti-nNOS Ser1417 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Katalógové číslo: (BOSSBS-19301R-A750)
Dodávateľ: BIOSS INC
Opis: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-0544R-A647

Anti-CIDEB Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalógové číslo: (BOSSBS-0544R-A647)
Dodávateľ: BIOSS INC
Opis: Activates apoptosis.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1351R-CY7

Anti-GZMB Rabbit Polyclonal Antibody (Cy7®)

Katalógové číslo: (BOSSBS-1351R-CY7)
Dodávateľ: BIOSS INC
Opis: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6477R-A350

Anti-FAS Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalógové číslo: (BOSSBS-6477R-A350)
Dodávateľ: BIOSS INC
Opis: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6477R-A555

Anti-FAS Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalógové číslo: (BOSSBS-6477R-A555)
Dodávateľ: BIOSS INC
Opis: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-5930R-A350

Anti-CENTG1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Katalógové číslo: (BOSSBS-5930R-A350)
Dodávateľ: BIOSS INC
Opis: GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion.
Merná jednotka: 1 * 100 µl
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