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Hľadali ste: transformat

Opravené na: "transformat"


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Green CMFDA ≥95% fluorescent dye

Dodávateľ: CAYMAN
Opis: Green CMFDA is a cell-permeable fluorescent probe that freely enters living cells, where it is transformed into a cell-impermeable, soluble, fluorescent compound. The resulting molecule does not affect cell viability or proliferation and stably fluoresces for at least 72 hours, allowing for its use in cell tracking. It is also transferred to daughter cells.

Image Unavailable-BNUB0786-500

Anti-TGFA Mouse Monoclonal Antibody (Purified) [clone: TG86]

Dodávateľ: BIOTIUM
Opis: This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this MAb is completely blocked by the peptide used for raising this antibody. TGF alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

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Image Unavailable-BOSSBS-12580R-CY5

Anti-ARID3B Rabbit Polyclonal Antibody (Cy5®)

Katalógové číslo: (BOSSBS-12580R-CY5)
Dodávateľ: BIOSS INC
Opis: ARID3B represents a member of a unique family of DNA-binding proteins that have roles in cell lineage gene regulation, cell cycle control, embryonic patterning and transcriptional regulation. ARID3B localizes to the nucleus and contains an AT-rich interactive domain (ARID) which has DNA-binding capabilities. Functioning as a transcription factor, ARID3B associates in a heterodimer with the related protein ARID3A and is believed to play an important role in neural crest survival during embryogenesis. In addition, ARID3B may participate in malignant transformation and neuroblastoma growth, suggesting a possible use of ARID3B as a tumor marker for neuroblastoma.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2969R-CY5.5

Anti-HPV33 E7 Rabbit Polyclonal Antibody (Cy5.5®)

Katalógové číslo: (BOSSBS-2969R-CY5.5)
Dodávateľ: BIOSS INC
Opis: E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity).
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2969R-A680

Anti-HPV33 E7 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalógové číslo: (BOSSBS-2969R-A680)
Dodávateľ: BIOSS INC
Opis: E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity).
Merná jednotka: 1 * 100 µl
Image Unavailable-BTIUBNC400062-100

Anti-Granulocyte Marker Mouse Monoclonal Antibody (CF640R) [clone: BM-2]

Dodávateľ: BIOTIUM
Opis: Recognizes 183 kDa protein with DNA-binding characteristics, which is identified as a myeloid specific antigen. It reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. This MAb reacts with early precursor and mature forms of human myeloid cells. It is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of this antigen is not clear, although it has been proposed that it may play a role in the differentiation of myeloid cells.

Image Unavailable-BTIUBNC940062-500

Anti-Granulocyte Marker Mouse Monoclonal Antibody (CF594) [clone: BM-2]

Dodávateľ: BIOTIUM
Opis: Recognizes 183 kDa protein with DNA-binding characteristics, which is identified as a myeloid specific antigen. It reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. This MAb reacts with early precursor and mature forms of human myeloid cells. It is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of this antigen is not clear, although it has been proposed that it may play a role in the differentiation of myeloid cells.

Image Unavailable-BTIUBNUB0061-100

Anti-Granulocyte Marker Mouse Monoclonal Antibody [clone: BM-1]

Dodávateľ: BIOTIUM
Opis: Recognizes 183 kDa protein with DNA-binding characteristics, which is identified as a myeloid specific antigen. It reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. This MAb reacts with early precursor and mature forms of human myeloid cells. It is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of this antigen is not clear, although it has been proposed that it may play a role in the differentiation of myeloid cells.

Image Unavailable-BTIUBNCB0061-100

Anti-Granulocyte Marker Mouse Monoclonal Antibody (Biotin) [clone: BM-1]

Dodávateľ: BIOTIUM
Opis: Recognizes 183 kDa protein with DNA-binding characteristics, which is identified as a myeloid specific antigen. It reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. This MAb reacts with early precursor and mature forms of human myeloid cells. It is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of this antigen is not clear, although it has been proposed that it may play a role in the differentiation of myeloid cells.

Image Unavailable-BTIUBNC880061-500

Anti-Granulocyte Marker Mouse Monoclonal Antibody (CF488A) [clone: BM-1]

Dodávateľ: BIOTIUM
Opis: Recognizes 183 kDa protein with DNA-binding characteristics, which is identified as a myeloid specific antigen. It reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. This MAb reacts with early precursor and mature forms of human myeloid cells. It is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of this antigen is not clear, although it has been proposed that it may play a role in the differentiation of myeloid cells.

Image Unavailable-BOSSBS-12580R-CY7

Anti-ARID3B Rabbit Polyclonal Antibody (Cy7®)

Katalógové číslo: (BOSSBS-12580R-CY7)
Dodávateľ: BIOSS INC
Opis: ARID3B represents a member of a unique family of DNA-binding proteins that have roles in cell lineage gene regulation, cell cycle control, embryonic patterning and transcriptional regulation. ARID3B localizes to the nucleus and contains an AT-rich interactive domain (ARID) which has DNA-binding capabilities. Functioning as a transcription factor, ARID3B associates in a heterodimer with the related protein ARID3A and is believed to play an important role in neural crest survival during embryogenesis. In addition, ARID3B may participate in malignant transformation and neuroblastoma growth, suggesting a possible use of ARID3B as a tumor marker for neuroblastoma.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-12580R-HRP

Anti-ARID3B Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalógové číslo: (BOSSBS-12580R-HRP)
Dodávateľ: BIOSS INC
Opis: ARID3B represents a member of a unique family of DNA-binding proteins that have roles in cell lineage gene regulation, cell cycle control, embryonic patterning and transcriptional regulation. ARID3B localizes to the nucleus and contains an AT-rich interactive domain (ARID) which has DNA-binding capabilities. Functioning as a transcription factor, ARID3B associates in a heterodimer with the related protein ARID3A and is believed to play an important role in neural crest survival during embryogenesis. In addition, ARID3B may participate in malignant transformation and neuroblastoma growth, suggesting a possible use of ARID3B as a tumor marker for neuroblastoma.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-12580R

Anti-ARID3B Rabbit Polyclonal Antibody

Katalógové číslo: (BOSSBS-12580R)
Dodávateľ: BIOSS INC
Opis: ARID3B represents a member of a unique family of DNA-binding proteins that have roles in cell lineage gene regulation, cell cycle control, embryonic patterning and transcriptional regulation. ARID3B localizes to the nucleus and contains an AT-rich interactive domain (ARID) which has DNA-binding capabilities. Functioning as a transcription factor, ARID3B associates in a heterodimer with the related protein ARID3A and is believed to play an important role in neural crest survival during embryogenesis. In addition, ARID3B may participate in malignant transformation and neuroblastoma growth, suggesting a possible use of ARID3B as a tumor marker for neuroblastoma.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-12580R-A488

Anti-ARID3B Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Katalógové číslo: (BOSSBS-12580R-A488)
Dodávateľ: BIOSS INC
Opis: ARID3B represents a member of a unique family of DNA-binding proteins that have roles in cell lineage gene regulation, cell cycle control, embryonic patterning and transcriptional regulation. ARID3B localizes to the nucleus and contains an AT-rich interactive domain (ARID) which has DNA-binding capabilities. Functioning as a transcription factor, ARID3B associates in a heterodimer with the related protein ARID3A and is believed to play an important role in neural crest survival during embryogenesis. In addition, ARID3B may participate in malignant transformation and neuroblastoma growth, suggesting a possible use of ARID3B as a tumor marker for neuroblastoma.
Merná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-12580R-A647

Anti-ARID3B Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalógové číslo: (BOSSBS-12580R-A647)
Dodávateľ: BIOSS INC
Opis: ARID3B represents a member of a unique family of DNA-binding proteins that have roles in cell lineage gene regulation, cell cycle control, embryonic patterning and transcriptional regulation. ARID3B localizes to the nucleus and contains an AT-rich interactive domain (ARID) which has DNA-binding capabilities. Functioning as a transcription factor, ARID3B associates in a heterodimer with the related protein ARID3A and is believed to play an important role in neural crest survival during embryogenesis. In addition, ARID3B may participate in malignant transformation and neuroblastoma growth, suggesting a possible use of ARID3B as a tumor marker for neuroblastoma.
Merná jednotka: 1 * 100 µl
Image Unavailable-BNC400787-500

Anti-TGFA Mouse Monoclonal Antibody (CF640R) [clone: P/T1]

Dodávateľ: BIOTIUM
Opis: This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this MAb is completely blocked by the peptide used for raising this antibody. TGF alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

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Zásoby tejto položky sú obmedzené, no môžu sa nachádzať v inom sklade blízko pri vás. Uistite sa prosím, že ste prihlásený/á na tejto lokalite, aby sa mohli zobraziť dostupné zásoby. Ak sa stále zobrazuje zavolajte a potrebujete pomoc, zavolajte nám prosím na číslo +43 1 97002 - 0.
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