Hľadali ste: Proteiny

Katalógové číslo: (ENZOENZPRT1120050)

Dodávateľ: ENZO LIFE SCIENCES

Opis: Produced in <i>E. coli</i>.

Merná jednotka: 1 * 50 µG

Predaj

Katalógové číslo: (SHBTPB-500-14)

Dodávateľ: SHENANDOAH BIOTECHNOLOGY

Opis: Cytokines for polarising mouse T cells into Th17 cells. T helper 17 cells (Th17) are a distinct type of T cell subset that are thought to be important in immunity against microbes at the epitilial and mucosal interfaces of the body. Disruption of the regular function or balance of Th17 cells is thought to be involved in several autoimmune diseases and/or opportunistic infections. Th17 cells are characterised by their ability to produce IL-17, IL-22 and IL-21. Th17 cells can be cultured from naive CD4+ T cells by culturing them in the presence of anti-CD3 and anti-CD28 stimulation with recombinant IL-6 and recombinant TGF-β 1. In some cases neutralising antibodies against IL-12, IL-4 and IFNγ are used along with recombinat cytokines IL-1 β, IL-21 and/or IL-23.

Merná jednotka: 1 * 1 KIT

New Product Predaj

Katalógové číslo: (SHBTPB-500-08)

Dodávateľ: SHENANDOAH BIOTECHNOLOGY

Opis: Cytokines for expansion and cell culture of mouse hematopoietic stem cells to progenitor cells. Hematopoietic stem cells are self renewing pluripotent cells often characterized by the expression of CD34. Studies have shown that decreased expression of CD34 tends to correlate with the decreased self renewal properties and pluripotent potential. Culturing CD34+ cells in a cytokine mixture of SCF, FLT-3 Ligand, IL-6 and IL-3 for short time periods allows rapid expansion of immature and more mature hematopoietic progenitor cells in cord blood or bone marrow preparations. If the goal is to only expand the most immature progenitor and stem cells, it is recommended that a combination of TPO, SCF and FLT-3 Ligand are used (Catalog: PB-500-04). Either cytokine combination can also be supplemented with other cytokines to promote specific lineages.

Merná jednotka: 1 * 1 KIT

New Product Predaj

Katalógové číslo: (ORIGTP313673)

Dodávateľ: ORIGENE TECHNOLOGIES

Opis: Purified recombinant protein of Homo sapiens myosin, heavy chain 6, cardiac muscle, alpha (MYH6).

Merná jednotka: 1 * 20 µG

New Product Predaj

Katalógové číslo: (NOVUNBP1-45318-0.1)

Dodávateľ: NOVUS BIOLOGICALS

Opis: OGG1, also known as 8-oxoguanine glycosylase, is a DNA glycosylase enzyme involved in base excision repair. This protein is the primary enzyme responsible for the excision of 7,8-dihydro-8-oxoguanine (8-oxoG), a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen species (ROS).

Merná jednotka: 1 * 0,1 mg

New Product Predaj

Dodávateľ: SHENANDOAH BIOTECHNOLOGY

Opis: Thrombopoietin (TPO) is a growth factor that is produced by liver and kidney tissues. TPO binds the TPO receptor (CD110) to promote megakaryocyte maturation, differentiation, and the production of platelets. Human TPO (CHO) contains a C-terminal 6x-polyhistidine (6xHis) tag.

New Product

Dodávateľ: SHENANDOAH BIOTECHNOLOGY

Opis: Epidermal Growth Factor (EGF) exerts its effects by binding to the EGF Receptor, a protein kinase that initiates the intracellular signaling. EGF is widely distributed in tissues like the kidney, cerebrum, prostate, and salivary glands. EGF acts as a potent factor in promoting cell division, and the phosphorylated receptor recruit adapter proteins like GRB2, which then activate complex downstream signaling cascades.

New Product

Dodávateľ: SHENANDOAH BIOTECHNOLOGY

Opis: GM-CSF is a hematopoietic growth factor with the ability to form colonies of granulocytes and macrophages. Enhances the number of circulating white blood cells and function of neutrophils and monocytes. Regulates multiple functions via transcription factors in the differentiated cells, including cell survival, proliferation, and maturation. Generates in vitro murine and human DC populations from bone marrow precursors and blood monocytes, respectively.

New Product

Dodávateľ: SHENANDOAH BIOTECHNOLOGY

Opis: IL-4 is an immunomodulatory cytokine that stimulates B cell proliferation and activates eosinophils, basophils, and mast cells.

New Product

Dodávateľ: SHENANDOAH BIOTECHNOLOGY

Opis: IL-3 is a species-specific cytokine and pleiotropic growth factor that promotes the survival, differentiation, and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil, and mast cell lineages.

New Product

Dodávateľ: SHENANDOAH BIOTECHNOLOGY

Opis: Stromal cell-derived factor-1 beta (SDF-1 β), also called CXCL12b, is one of two SDF-1 splice variants made by a wide variety of cells upon stimulation by inflammatory cytokines such as TNF, IL-1, and LPS. SDF-1 β signals through the G protein-coupled receptor CXCR4 to recruit activated leukocytes.

New Product

Katalógové číslo: (SHBTPB-500-01)

Dodávateľ: SHENANDOAH BIOTECHNOLOGY

Opis: Cytokines for expansion and cell culture of mouse hematopoietic stem cells. Hematopoietic stem cells are self renewing pluripotent cells often characterized by the expression of CD34. Studies have shown that decreased expression of CD34 tends to correlate with decreased self renewal properties and pluripotent potential. Culturing CD34+ cells in a cytokine mixture of TPO, SCF, and FLT-3 Ligand for short time periods allows CD34+ cells to proliferate without decreasing CD34 expression, thus retaining their stem cell properties.

Merná jednotka: 1 * 1 KIT

New Product Predaj

Katalógové číslo: (ORIGTP723730)

Dodávateľ: ORIGENE TECHNOLOGIES

Opis: This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2008).

Merná jednotka: 1 * 10 µG

Predaj

Dodávateľ: ORIGENE TECHNOLOGIES

Opis: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues.

Katalógové číslo: (PRSI91-807)

Dodávateľ: PROSCI

Opis: Tumor necrosis factor receptor superfamily member 19L (TNFRSF19L), also known as Receptor expressed in lymphoid tissues and RELT, is a member of the TNF-receptor superfamily. TNFRSF19L is a single-pass type membrane protein and contains one TNFR-Cys repeat. TNFRSF19L is highly expressed in spleen, lymph node, thymus, peripheral blood leukocytes, bone marrow and fetal liver. It has been shown TNFRSF19L activates the NF-kappaB pathway and selectively binds TNF receptor-associated factor 1 (TRAF1). TNFRSF19L is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response.

Merná jednotka: 1 * 0,05 mg

New Product Predaj

Dodávateľ: Apollo Scientific

Opis: Human recombinant Fetuin-B