Hľadali ste: Protilátky

Katalógové číslo: (BOSSBS-12508R-CY7)

Dodávateľ: BIOSS INC

Opis: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-12508R-CY5)

Dodávateľ: BIOSS INC

Opis: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-11544R-CY5)

Dodávateľ: BIOSS INC

Opis: Bcl-11a genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-4122R-A647)

Dodávateľ: BIOSS INC

Opis: MAX is a basic helix-loop-helix, leucine zipper protein that forms heterodimers with MYC and MAD. It is involved in regulating gene expression.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-4121R-A488)

Dodávateľ: BIOSS INC

Opis: Exendin 4 is a 39 amino acid peptide found in venom from the Gila monster Helicoderma suspectum. It is a member of the glucagon secretin family of peptide hormones and neuropeptides. Exendin 4 is a potent agonist of the GLP1 receptor and hence a potent stimulator of insulin secretion.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-11544R-HRP)

Dodávateľ: BIOSS INC

Opis: Bcl-11a genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-4122R-CY3)

Dodávateľ: BIOSS INC

Opis: MAX is a basic helix-loop-helix, leucine zipper protein that forms heterodimers with MYC and MAD. It is involved in regulating gene expression.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-15573R-A750)

Dodávateľ: BIOSS INC

Opis: Ig delta chain C region is an allelic product of the human IGHD gene. The two known IGHD alleles, IGHD*01 and IGHD*02, respectively produce isoforms 1, a secreted protein, and 2, a single-pass type I membrane protein. A member of the adaptive immune system, IgD are monomers expressed by activated B cells. Containing 3 Ig-like (immunoglobulin-like) domains, IgD chain C is located on chromosome 14 within the human heavy chain locus, lying on the 3? side of the IgM chain C region from the V-D-J cassette. Polyadenylation at certain sites along the heavy chain locus likely effects the mechanism that determines the alternative splicing event which results in the expression of either IgD chain C or IgM chain C. Some studies have suggested that antigenic coactivation of IgD+ B cells can have a negative influence on bone resorption during infectious events.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-7746R-CY7)

Dodávateľ: BIOSS INC

Opis: Together with dynein may be involved in spindle assembly and cytokinesis.Tissue specificity:Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-15574R-A350)

Dodávateľ: BIOSS INC

Opis: IGIP.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-15533R-A350)

Dodávateľ: BIOSS INC

Opis: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-9061R-A680)

Dodávateľ: BIOSS INC

Opis: Teneurin-3, also known as Ten-3, TNM3 or ODZ3, is a 2,699 amino acid single-pass type II membrane protein that contains 25 YD repeats, 8 EGF-like domains, 5 NHL repeats and one teneurin N-terminal domain. Localised to the membrane and expressed in brain, testis and ovary, Teneurin-3 exists as a disulfide-liked homodimer that is thought to function as a cellular signal transducer. Additionally, Teneurin-3 may participate in eye-specific patterning in the visual pathway and is required for aligned binocular vision. The gene encoding Teneurin-3 maps to chromosome 4. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes, one of which is the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-9062R-CY5)

Dodávateľ: BIOSS INC

Opis: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-9062R-FITC)

Dodávateľ: BIOSS INC

Opis: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-1223R-A488)

Dodávateľ: BIOSS INC

Opis: This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.

Merná jednotka: 1 * 100 µl

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Katalógové číslo: (BOSSBS-1223R-A350)

Dodávateľ: BIOSS INC

Opis: This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.

Merná jednotka: 1 * 100 µl

Predaj