Lavendustin A 98
Dodávateľ: ENZO LIFE SCIENCES
EGFR inhibitor
Cell permeable tyrosine kinase inhibitor with little effect on cAMP-dependent protein kinase (PKA) or protein kinase C (PKC). Potent and selective inhibitor of the EGF receptor tyrosine kinase (IC50=11nM). Binds to a site on the kinase which is distinct from the ATP and peptide substrate binding sites. Inhibits EGF-induced proliferation of cultured human myometrial smooth muscle cells and suppresses VEGF-induced angiogenesis in rats. Effective at 10µM in cultured leech neurons. Also inhibits NMDA-stimulated cGMP production.
Vzorec:
C₂₁H₁₉NO₆ Mw: 381.384 g/mol |
Číslo MDL:
MFCD00153822 Číslo CAS: 125697-92-9 |
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