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Anti-FCGR3A Mouse Monoclonal Antibody (CF647) [clone: HO-80]

Dodávateľ: BIOTIUM
BNC471056-500 BNC471056-100
BNC471056-500EA 638.49 EUR
BNC471056-500 BNC471056-100
Anti-FCGR3A Mouse Monoclonal Antibody (CF647) [clone: HO-80]
Protilátky
This antibody recognizes CD16 (FcγRIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80 kDa. Two similar genes represent CD16, CD16A (FcγRIIIA), which exists as a hetero-oligomeric polypeptide-anchored form in macrophages and NK cells and CD16B (FcγRIIIB), which exist as a monomeric GPI-anchored form in neutrophils. Furthermore, there are two known polymorphisms of CD16B, NA-1 and NA-2. Individuals homozygous for NA-2 show a lower phagocytic capacity compared with NA-1. CD16 binds IgG in the form of immune complexes and shows preferential binding of IgG1 and IgG3More Product Information
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