Spermine-(N,N'-bis(3-aminopropyl)-1,4-butanediamine) ≥97%, colorless solid
Dodávateľ: MP Biomedicals
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Nebezpečí
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Synonymá:
N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine), Spermine
Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine through the addition of aminopropyl group to spermidine by spermine synthase. It is found as a polycation at physiological pH.
Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Soluble in water (1% w/v), lower alcohol, chloroform; practically insoluble in ether, benzene, petroleum ether.
Pozor: Research Use Only (RUO). Desiccate, store under nitrogen.
Vzorec:
C₁₀H₂₆N₄ Teplota varu: 141…142 °C (0,5 mmHg) Teplota tavenia: 28…30 °C (lit.) Skladovacia teplota: Refrigerator |
Číslo MDL:
MFCD00008215 Číslo CAS: 71-44-3 |
Výsledky špecifikačného testu
Identity Test | Passes |
Purity | ≥97% |
FTIR | Conforms to Standard |
pH (0.5% aq soln) | 11 - 14 |
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