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Anti-PRKDC Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Dodávateľ: BIOSS INC
BS-10994R-A647
BOSSBS-10994R-A647EA 1018.63 EUR
BOSSBS-10994R-A647
Anti-PRKDC Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Protilátky
Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localization of DNAMore Product Information
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