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Anti-CD4 Rat Antibody (redFluor™ 710) [clone: RM4-5]

Dodávateľ: TONBO BIOSCIENCE
80-0042-U100 80-0042-U025
80-0042-U100EA 156.62 EUR
80-0042-U100 80-0042-U025
Anti-CD4 Rat Antibody (redFluor™ 710) [clone: RM4-5]
Protilátky
The RM4-5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta2-domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.

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